A neighbor is a medical transcripitionist. She worked from home for years and was recently laid off, proving working at home can have the same risks as all others.
A friend has worked as a mystery shopper and also as an independent contractor attending to retail displays. Both are legitimate, reliable sources of income but provide limited earning potential.
In this era of non-cooking, another friend prepares home-cooked meals and sells them to friends and neighbors. There must be a lot of demand for this, as she has had a business doing this for quite some time and is a mediocre cook.
This same person also works as an independent sales rep for several retailers. This requires a lot of time and effort, and an extensive network of friends and acquaintances, but can work given time, effort, and salesmanship.