Do you mean for Google advertisers?
If you do, then the answer is: Yes, and no.
Since Google reworked it's system of displaying ads to surfers, some ads are based on the search history of the user, NOT the content of your page. So if a searcher was looking for "New Cars" and clicked on a search result, then found a link to your hub about cooking from a link on the Hub network, the ads on your page very much may have to do with cars, not cooking. So the answer for this part of your question is you can't control the CPM rate, or even the subject matter of the ads on your page.
The "Yes" part of your question is that if you write about high CPM topics and the user finds your hub through Google, then those higher priced CPM ads MAY be there.
If you want to increase your ad revenue, the best thing to do is to write good and useful content in a subject area that requires additional purchases (ie, reviews for products) and to create organic backlinks to your content.
Backlinks increase your Google PR and also help to insure that uses are actually actively searching for the topic you are discussing.