Multiple Choice Questions on Myasthenia Gravis

Multiple Choice Questions on Myasthenia Gravis

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Myasthenia Gravis-Introduction:

Myasthenia Gravis is an auto immune disease of the neuro muscular junction. It is a chronic disease where an auto immune process destroys a good number of acetylcholinereceptors at the neuro muscular junction. More specifically a variable number of acetylcholine receptors at the post synaptic muscle membrane are destroyed due to auto immune process in Myasthenia Gravis. People with Myasthenia Gravis also may have other autoimmune diseases.

Easy fatigability and muscle weakness of some of the voluntary muscles are the characteristic features of the disease. Muscles innervated by the motor nuclei of the brain stem are more commonly affected (extra ocular muscles, muscles of mastication, facial muscles and muscles of swallowing and speech). The muscle weakness increases during periods of activity and improves after rest.

Myasthenia Gravis-Ptosis

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Which one of the following is an autoimmune disease affecting the neuromuscular junction?

  • Myasthenia Gravis

  • Parkinson’s Disease

  • Multiple Sclerosis

  • All of the above

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    Answer: Myasthenia Gravis

Which one of the following is NOT a brain disorder and brain functions normally?

  • Alzheimer’s Disease

  • Myasthenia Gravis

  • Parkinson’s Disease

  • Multiple Sclerosis

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Answer: Myasthenia Gravis

Which one of the following diseases is characterized by fluctuating muscle weakness and fatigability?

  • Alzheimer’s Disease

  • Myasthenia Gravis

  • Parkinson’s Disease

  • Multiple Sclerosis

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Answer: Myasthenia Gravis

Myasthenia Gravis results from the decrease in the number of receptors of following neurotransmitter at the motor endplate?

  • Acetylcholine

  • Dopamine

  • Gamma amino butyric acid

  • Serotonin

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Answer: Acetylcholine

Tensilon Test

Myasthenia Gravis is more common among

  • Men

  • Women

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Answer: Women

Tensilon test is diagnostic of one of the following diseases

  • Alzheimer’s Disease

  • Myasthenia Gravis

  • Parkinson’s Disease

  • Multiple Sclerosis

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Answer: Myasthenia Gravis

Difficulty speaking found in patients with Myasthenia Gravis is known as

  • Dysarthria

  • Dysphagia

  • Diplopia

  • Ptosis

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Answer: Dysarthria

Difficulty swallowing found in patients with Myasthenia Gravis is known as

  • Dysarthria

  • Dysphagia

  • Diplopia

  • Ptosis

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Answer: Dysphagia

Myasthenia Gravis

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Drooping eyelids found in patients with Myasthenia Gravis is known as

  • Dysarthria

  • Dysphagia

  • Diplopia

  • Ptosis

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Answer: Ptosis

Double vision found in patients with Myasthenia Gravis is known as

  • Dysarthria

  • Dysphagia

  • Diplopia

  • Ptosis

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Answer: Diplopia

Which of the following group of muscles is affected by Myasthenia Gravis?

  • Skeletal muscles

  • Smooth muscles

  • Cardiac muscle

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Answer: Skeletal muscles

Which of the following is true with regard to the clinical presentation of Myasthenia Gravis?

Weakness worsens as the day progresses

  • Weakness is severe in the morning

  • Limb weakness is more severe distally than proximally

  • Weakness is not affected by the level of activity

  • Weakness progresses in severity very rapidly

  • Weakness generally starts in the limb muscles and then spread to facial muscles and ocular muscles

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Answer: Weakness worsens as the day progresses

USMLE Step 1 Tutorial - Myasthenia Gravis

Which of the following groups of drugs may trigger an exacerbation of Myasthenia Gravis?

  • Aminoglycosides, Ciprofloxacin, Chloroquine

  • Procaine, Lithium, Phenytoin

  • Beta-blockers, Procainamide, Statins

  • All of the above

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Answer: All of the above

The peak incidence of Myasthenia Gravis is

  • Third decade in females and sixth or seventh decade in males

  • Third decade in males and sixth or seventh decade in females

  • Second decade in males and sixth or seventh decade in females

  • Second decade in females and sixth or seventh decade in males

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Answer: Third decade in females and sixth or seventh decade in males

What are the management measures of Myasthenia Gravis

  • Anticholinesterase (AchE) inhibitors

  • Immunomodulating agents

  • Intravenous immune globulin (IVIg)

  • Plasmapheresis

  • Thymectomy

  • All of the above

  • ---------------------------------------------

Answer: All of the above

One of the following is an acetyl cholinesterase used in the treatment of Myasthenia Gravis

  • Pyridostigmine

  • Azathioprine

  • Cyclosporine A

  • Methotrexate

Answer: Pyridostigmine

Myasthenia gravis Nursing Considerations & Patho Part 1

Patient Teaching for Myasthenia Gravis

  • A patient diagnosed with Myasthenia Gravis can have a normal life with some lifestyle modifications. With the current treatments available, Myasthenia Gravis is not considered as a grave disease anymore.

  • A medic alert /bracelet indicating the diagnosis is advisable when the patient travels

  • Medications should be taken as prescribed and follow ups as advised by the specialist to be continued

  • If the muscles of chewing and swallowing are affected, the medications should be taken early enough to provide strengths for the muscles while eating

  • Select appropriate diet preferably soft diet if you have difficulty in swallowing. Soft diet will facilitate swallowing and prevent aspiration

  • Plan your activities and rest periods

  • Prioritize the activities so that you complete essential activities before feeling fatigued

  • Avoid stressors to the body like extreme temperatures, excessive exposure to sunlight and emotional stresses

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Comments 13 comments

thumbi7 profile image

thumbi7 16 months ago from India Author

Hi Peggy

Thanks for the visit and comment. For all my mcq hubs most visitors are students. They find it useful to study. For anyone outside medical field, it might be bit difficult to understand. Thanks again


Peggy W profile image

Peggy W 16 months ago from Houston, Texas

This is a nice format to teach people about this medical condition. Not sure everyone outside of the medical field would understand all the terminology...but they can look it up if interested. The patient teaching would be most helpful to understand if one knows of anyone suffering with this condition.


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi Vellur

Thanks for the visit and comment


Vellur profile image

Vellur 2 years ago from Dubai

A great hub and quiz about Myasthenia Gravis, thank you for sharing.


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi ChitrangadaSharan

thanks for the visit


ChitrangadaSharan profile image

ChitrangadaSharan 2 years ago from New Delhi, India

I liked the idea and the format of the hub! At the same time it is very educative about a difficult medical condition.

Nice and well researched hub, voted up!


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi ologsinquito

Thanks for the visit


ologsinquito profile image

ologsinquito 2 years ago from USA

It's a very sad disease. I wish there were more progress, so that the diagnosis is not a death sentence.


tirelesstraveler profile image

tirelesstraveler 2 years ago from California

Your multiple choice format is a creative way to educate us about difficult things like Myasthenia Gravis. It was easy to follow. I had no idea so many common drugs are bad for someone with MG


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi DDE

Thanks for the visit


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi mylindaelliott

The person you knew may be having Myasthenia Gravis. If you still have contacts please talk to that person and encourage him to go for a health check up


DDE profile image

DDE 2 years ago from Dubrovnik, Croatia

Multiple Choice Questions on Myasthenia Gravis is informative and I found this hub to most helpful to me. Testing my knowledge on Myasthenia Gravis allowed me to learn more on this health issue.


mylindaelliott profile image

mylindaelliott 2 years ago from Louisiana

I believe I know someone who had this. Well I knew them years ago. I never realized what they had. I'm not sure she knew either.

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