Multiple Choice Questions on Parkinson’s Disease

Parkinson's Disease

Parkinson's Disease

Source

Parkinson’s Disease –Introduction

Parkinson’s Disease, a movement disorder was first described by James Parkinson in 1817. It is a neurodegenerative disorder caused by the scarcity of dopamine producing neurons.

Tremor, rigidity and bradykinesia are the cardinal symptoms of full blown Parkinson’s disease. Initially the patients may only have slowness. Altered body image causes anxiety and depression in most of these patients.

The common cause of chronic progressive parkinsonism is

  • Gene mutation

  • Toxins

  • Trauma

  • All of the above

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Answer: All of the above

The peak age of onset for Parkinson’s Disease is in the following decade

  • Third

  • Fourth

  • Fifth

  • Sixth

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Answer: Sixth

Parkinson’s Disease is more commonly seen among

  • Men

  • Women

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Answer: Men

Implication of autophagy deregulation in Parkinson's Disease (PD)

Source

What is the usual blinking rate per minute in a human being?

  • 12 to 20

  • 15 to 25

  • 18 to 28

  • 21 to 31

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Answer: 12 to 20

What is the blinking rate per minute for a patient with Parkinson’s Disease?

  • 5 to 10

  • 12 to 17

  • 19 to 24

  • 26 to 31

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Answer: 5 to 10

The characteristic tremor of Parkinson’s disease is described as

  • Alternating

  • Pill-rolling

  • Resting

  • All the above

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Answer: All the above

Parkinson's Disease

Micrographia of Parkinson’s disease is

  • Hurried walking

  • Slowness of movement

  • Small handwriting

  • Soft speech

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Answer: Small handwriting

The characteristic tremor of Parkinson’s disease usually involves

  • Arm

  • Eyelids

  • Hand

  • Jaw

  • Tongue

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Answer: Hand

Bradykinesia of Parkinson’s disease is

  • Hurried walking

  • Slowness of movement

  • Small handwriting

  • Soft speech

----------------------------------------------

Answer: Slowness of movement

Surgery for Parkinson's Disease-Deep Brain Stimulation

Source

The part of the brain most affected in Parkinson’ Disease is

  • Corpus striatum

  • Putamen

  • Substantia nigra

  • Thalamus

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Answer: Substantia nigra

Eosinophilic cytoplasmic inclusions seen in the brain cells of a patient with Parkinson’ Disease are

  • Golgi bodies

  • Lewy bodies

  • Paschen bodies

  • All of the above

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Answer: Lewy bodies

Which of the following genes are linked to Parkinson's Disease?

  • SNCA and PARK2

  • PARK2 and PARK7

  • PARK7 and PINK1

  • PINK1 and LRRK2

  • All of the above

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Answers: All of the above

Which of the following tests aid to determine the levels of dopamine in the brain cells of a patient with Parkinson’s Disease ?

  • MRI

  • Olfactory testing

  • PET scan

  • Sonography

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Answer: PET scan

Which is the drug of choice for the symptomatic treatment of Parkinson's Disease?

  • Amantadine

  • Anticholinergic

  • Dopamine

  • Levodopa

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Answer: Levodopa

Why is dopamine not the drug of choice for symptomatic treatment of Parkinson ’s Disease when the symptoms of Parkinson’s disease are caused by loss of dopamine

  • Dopamine cannot cross the blood brain barrier

  • Dopamine has serious side effects

  • Dopamine is less tolerated

  • All of the above

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Answer: Dopamine cannot cross the blood brain barrier

Levodopa is used along with Carbidopa in the treatment of Parkinson’Disease because Carbidopa

  • Aids Levodopa to cross blood brain barrier

  • Blocks the early conversion of Levodopa into dopamine

  • Enhances the absorption of levodopa

  • All of the above

--------------------------------------------------------------

Answer: Blocks the early conversion of Levodopa into dopamine

Parkinson's Disease

What are the pharmacological treatment options for a patient with Parkinson ’s Disease who has to be on nil per oral?

  • Transdermal rotigotine

  • Transdermal apomorphine

  • Orally disintegrating carbidopa-levodopa

  • All the above

------------------------------------------------

Answer: All the above

The symptom of Parkinson’s Disease which is less likely to respond to Levo dopa is

  • Tremor

  • Rigidity

  • Akinesia

  • Postural instability

---------------------------------------

Answer: Postural instability

Increased risk of hip fractures in elderly patients with Parkinson’s Disease on Levodopa is due to elevation in serum

  • Calcium

  • Homocysteine

  • Vit D

  • All of the above

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Answer: Homocysteine

MAO-B inhibitor in the treatment of Parkinson’s Disease

  • Converts levodopa to dopamine

  • Delays the metabolism of dopamine

  • Triggers dopamine receptors

  • All of the above

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Answer: Delays the metabolism of dopamine

One of the following categories of drugs used in the treatment of Parkinson’s Disease has constipation as a common side effect

  • Dopamine agonist

  • MAO Inhibitor

  • Anticholinergic

  • COMT inhibitors

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Answer: Anticholinergic

Bromocriptine used in the treatment of Parkinson’s disease is a

  • Dopamine agonist

  • MAO Inhibitor

  • Anticholinergic

  • COMT inhibitors

-----------------------------------------

Answer: Dopamine agonist

The antiviral agent with mild antiparkinsonian activity is

  • Amantadine

  • Anticholinergic

  • Dopamine

  • Levodopa

---------------------------------

Answer: Amantadine

What are the New Approaches to the Treatment of Parkinson’s Disease?

Another new agent found to be helpful in the treatment of Parkinson’s disease is nicotine. It is shown to slow the degeneration of neurons. Melatonin (a serotonin derivative) has also shown to reduce the production of neurodegenerative free radicals. Not much is known about the effects of nicotine and melatonin on a patient with Parkinson’s Disease.

The multiple choice questions listed above are meant for students of medicine, nursing or allied health to understand and learn about the disease.

Hence if you are a patient with Parkinson’s Disease please don’t start self-medicating yourself. Instead please consult a specialist and follow the instructions.

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Comments 18 comments

M.Aljamel 2 months ago

Thanks for all the great information


thumbi7 profile image

thumbi7 16 months ago from India Author

Hi Nikki

Thanks for the visit and comment


Nikki D. Felder profile image

Nikki D. Felder 16 months ago from Castle Hayne, N.C.

A fiend of mine battled with ALS or Lou Gehrig's disease. I had that and Parkinson mixed up. Thank you for clearing this up and an informative article!


thumbi7 profile image

thumbi7 16 months ago from India Author

Hi peachpurple

Thanks for the visit and comment :)


peachpurple profile image

peachpurple 16 months ago from Home Sweet Home

I like the way you putvin questions n answers, easier to read, thanks


thumbi7 profile image

thumbi7 17 months ago from India Author

Hi Stella

Thanks for the visit


ladyguitarpicker profile image

ladyguitarpicker 17 months ago from 3460NW 50 St Bell, Fl32619

Hi, Interesting about the nicotine, and I also use melatonin for sleep. Have had this for about 5 years. I smoked years ago but not anymore. A useful hub with good information. Stella


thumbi7 profile image

thumbi7 17 months ago from India Author

Hi Deb,

Thanks for the visit and comment


aviannovice profile image

aviannovice 17 months ago from Stillwater, OK

Having known several people with Parkinson's, I was quite curious to see this. Knowing a bit about the disease as well, I hoped to further my knowledge, too. Great introductory material.


thumbi7 profile image

thumbi7 17 months ago from India Author

Hi Anushka Britto

Thanks for the visit and comment


Anushka Britto profile image

Anushka Britto 17 months ago from Auckland

Wow was really interesting reading this - my grand dad has parkinsons and I understand so much more now. Thank you


chateaudumer profile image

chateaudumer 2 years ago from Northern California and the Philippines

Excellent hub, voted up!


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi tobusiness

Thank you very much for those wonderful words


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K

What a brilliant way to pass on this very useful information! Excellent hub.

Well done, Up and sharing.


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi cam8510

Thank you so much for the visit


cam8510 profile image

cam8510 2 years ago from Columbus, Georgia until the end of November 2016.

Excellent article thumbi7. Thanks for all the great information.


thumbi7 profile image

thumbi7 2 years ago from India Author

Hi DDE,

Thanks for the visit. This quiz is meant for students of health sciences. It is OK if you don't know the answers.


DDE profile image

DDE 2 years ago from Dubrovnik, Croatia

Multiple Choice Questions on Parkinson’s Disease very interesting and I had no idea of most the Qs and As of this puzzle definitely well informed health information.

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