I believe that the traits of a human being - that is, our over-confidence, our thinking that we are superior to everything on this planet, our selfishness etc. - combined with our advanced intellect means that we have indeed come to 'abuse' our knowledge, as you say. For example, man became clever enough to design advanced technology, but it is this technology which is destroying the Earth. And despite being aware of this, we continue to produce such products because we feel good about ourselves for having 'achieved' such a task. This is abuse of knowledge. Knowledge should be used wisely, carefully and in the right situations.
I am not religious, but I remember my Nanna used to always say: 'It says in the Bible that man will destroy the Earth...'. Maybe it was right?