I'm not quite sure how to read your question.
Have I ever given up a bad habit? Not as many as I should have.
Have I given up on a person arriving at a reasonable answer/solution? Yes, and usually sadly.
Have I given up on pursuit of a personal goal or task? Can't remember consciously doing so, but may well have by default.
Have I ever felt like suicide? No. Tomorrow can always be a better day, as long as there is a tomorrow.