How A Tomato Pill Can Improve Blood Vessel Function To Reduce The Number of Death Globally.

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Heart Failure set to Increase

According to the American Heart Association, Death in the US from hearth failure increased by 28% from 1994 to 2004 and is set to continue at approx. this rate into 2030.
According to the American Heart Association, Death in the US from hearth failure increased by 28% from 1994 to 2004 and is set to continue at approx. this rate into 2030. | Source

Eat for a Healthier Heart

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Cardiovascular Diseases and Risk Factors

Cardiovascular disease (CVD) is an umbrella term used to describe all diseases of the heart and circulation. They include heart failure, stroke, congenital heart disease and coronary heart diseases (CHD) such as angina and myocardial infarction (MI).

CVDs are the leading cause of death and disability globally, one of the main causes of deaths in the US since 1921. In 2003, CVDs accounted for 34.4% of the 2.4 million deaths in the US.

According to the British Heart Foundation, In 2010, the number of fatalities from CVDs was 180,000 in the UK, 80,000 of these deaths were caused by CHD, around 49,000 due to strokes. Premature deaths from CVDs accounted for 46,000, of which 68% were men.

There are around 152,000 cases of strokes in the UK every year, more than one every 5 minutes, one in every five strokes are fatal. Premature death rates from stroke are around three times higher in the most deprived areas. Stroke causes about 7% of deaths in men and 10% of deaths in women, the higher rate for women, may be because women tend to live longer than men.

According to the CDC, Under the age of 60, women who have a heart attack are more likely to die than men who have a heart attack. In 2009 to 2010, about 47% of adults had, at least, one of three risk factors for cardiovascular disease:

  • Uncontrolled high blood pressure
  • Uncontrolled elevated levels of low-density lipoproteins (LDL) cholesterol
  • Current Smoking

Although the statistics are alarming, the news is not all bad. In the last ten years, the death rate from CHD in England has fallen by 45% in people under the age of 65 years.

Deaths from coronary attack have halved since 2002, the incidence of heart attack or myocardial infarction (MI) have fallen in all regions of England. Stroke mortality rates have halved over the last 20 years, achieving mortality targets as set by successive governments.

Death rates from CHD are higher in areas of greatest deprivation such as Scotland and the North of England.

Eliminating the Risk Factor

The improved mortality rate for CVDs over the last ten is due to better management of both the condition and the risk factors. Prescriptions for lipid-lowering and antihypertensive drugs have largely increased. Percutaneous coronary interventions have helped to improve survival rate after a Coronary event and are now common place. Smoking has fallen dramatically in recent years. We eat less fat, less sugar, less salt and continues to up our fruit and vegetable intake. As a nation, we are exercising more and are more aware of what we are eating and taking into our bodies.

Smoking

According to research studies, around 50% of the improved mortality rate of CVDs is due to prevention such a reduction in smoking. It is interesting that the prevalence of smoking among adults is also lower in England and higher in more deprived areas.

Most people are aware that smoking increases the risk of CHD; a 50-year study found that CHD mortality was about 60% greater in smokers and 80% higher in heavy smokers when compared with non-smokers. The study concluded that their habit will eventually kill about 50% of all regular smokers.

In England, there is little variation in smoking rates by region, but rates are marginally higher in the North. Rates in Scotland, Wales and Northern Ireland, are greater than England.

England (20%)

Scotland (24%)

Wales (25%)

Northern Ireland (24%)

The Incidence of angina in men appears highest in Wales, for women, it is greater in Scotland. However, for both sexes, the rate of angina is lowest in England. While the decline in death rate in the UK is encouraging, we are still lagging behind countries like Australia (48% ) and Norway (54%).

The reduction in the incidence of CHD in the UK did not happen by accident; governments have been setting some very ambitious targets for reducing the number of deaths throughout the UK, especially in the high risk 40 -60 age group.

Diet

As a result of education, more people are eating healthier foods, but there is still room for improvement. While a large number of people are eating the recommended 5 to 7 portions of fruit and vegetables per day, only one-fifth of boys and girls aged 5 to 15 are consuming sufficient quantities.

Eating significant amounts of fruit and vegetables can reduce the risk of stroke by a huge 30%, the more we consume, the lower the risks, every additional portion we eat, reduce the risk by 5%.

Exercise

More of us take regular exercise, although there are still more men than women meeting the government's recommendations for physical activities. Well done men, but don't rest on your laurels, still only half of the men in the UK are meeting the recommendations.

Alcohol a Risk Factor

In 2010, 36% of men and 28% of women regularly exceeded the recommended alcohol intake. While there has clearly been an improvement in our health, there is still a long way to go.

Obesity

People who are overweight or obese, have a higher risk of developing coronary heart disease. The World Health Organisation's (WHO) definition of obesity is:

  • A BMI greater than or equal to 25 is overweight
  • A BMI greater than or equal to 30 is obesity

Body Mass Index (BMI) is a calculation used to indicate whether a person has a healthy weight for their height. BMI is calculated by dividing the weight in kilograms by the height in meters squared.

BMI is the same as male and female. However, since it may not correspond to the same degree of fatness in different people, it should be seen as a rough guide only.

More than a quarter of adults in England are obese, in the US more than one-third of the adult population is obese. Obesity and overweight are significant risks for global deaths. Approximately 3.4 million adults die each year as a result of being overweight or obese.

More than 40 million children under the age of 5 were overweight or obese in 2012. Obesity was once considered a problem mainly for high-income countries but is now on the rise in low and middle-income countries especially in the urban areas.

Research shows that individuals who fit moderate activity like walking, into their daily life, tends to burn more energy than those who make weekly visits to the gym. For short journeys, walking instead of driving or using public transport can be extremely beneficial to health. Walking 10,000 steps a day can burn up to 400 calories.

Diabetes

Researchers have demonstrated a strong link in individuals with large waist circumference and an increased risk of developing type 2 diabetes, independent of a person's BMI. A Large waist size is defined as over 40 inches/102cm for men and over 34.5 inches/88 cm for women.

The Diabetes UK risk score now includes waist size as one of the measures. Diabetes is a high-risk factor for CVDs. Uncontrolled diabetes causes damages to the blood vessels, which makes them more susceptible to damages from atherosclerosis and hypertension.

People with diabetes are 2 to 3 times more likely to develop CVDs that continues to be a leading cause of deaths for people with diabetes.

Obesity rate continues to rise

Why Lycopene may be beneficial to Health

  • Lycopene is a powerful antioxidant found in the red pigment in the skin of ripe tomatoes and some fruits and vegetables
  • Predicted to potentially, extend and possibly save lives
  • Ateronon is a lycopene supplement, but unlike natural lycopene, it is easy to absorb
  • Ateronon is marketed and sold for around £35/month
  • Each pill is the equivalent of eating approximately three kilos of tomatoes/day
  • Pills may increase blood flow by 50% in patients with cardiovascular diseases
  • A 2013 Finnish study found that men with lowest levels of lycopene were up to 60% more likely to have a heart attack (Myocardial infarction or MI)
  • Result in the British Journal of Nutrition showed, that eating foods rich in lycopene regularly, over a period of eleven years can reduce the risk of coronary heart disease by 26%, but had no effect on the chances of strokes
  • The antioxidant properties of ripe tomatoes have been long associated with reducing the risk of prostate cancer in men
  • Mediterranean diet rich in lycopene and olive oil is known to decrease the risk of heart attack and stroke
  • Lycopene may also be beneficial in reducing the risk of other chronic diseases, but more comprehensive research is needed.

New Lycopene Tomato Pill for preventing Coronary Heart disease

A new tomato based health pill was recently launched in the UK. Scientists believe that the pill could potentially save and extend lives of millions of people throughout the world.

According to British scientists, the lycopene-rich pill work by widening blood vessels, cleaning and unclogging fat from arteries to prevent cardiovascular disease.

The lycopene supplement known as "Ateronon" is made by Cambridge Theranostics, linked to Cambridge University. The pill contains a version of the naturally occurring carotenoid compound lycopene. Lycopene can be significant in the treatment of high blood cholesterol and atherosclerosis.

When LDL cholesterol (bad cholesterol) is oxidized, it causes a build-up of plaque that fur up the arteries. Ateronon is said to be clinically proven to help inhibit the oxidation process of LDL cholesterol.

Lycopene is a natural chemical compound found in some fruits and vegetables. The skin of ripe tomatoes is a rich source of the compound.

A small controlled randomised trial was done by the University of Cambridge, Cambridge University Hospital NHS Foundation Trust in the UK. The test also included The University of Tartu, in Estonia, funded by the Welcome Trust. The British Heart Foundation and others. The study found that the blood vessels in people with cardiovascular disease who took statins became dilated to a greater degree, improving by 53% when treated with acetylcholine, after taking lycopene every day for two months, rather than a placebo.

There were no apparent changes on the blood vessels and endothelial function of healthy volunteers after lycopene treatment.

Lycopene is said to be able to clean out almost all the harmful fats in the blood within eight weeks. The controlled trial investigated the effects of lycopene in tomatoes and other fruits and vegetables on the blood vessels of patients with cardiovascular disease.

Some of the participants were taking statins; others were healthy volunteers with no history of CVD. Clinical tests on lycopene and its effects on cardiovascular diseases and other chronic conditions are ongoing.

Lycopene is well known as a powerful anti-oxidant able to remove potentially damaging free radicals from the body, but the new study shows that lycopene can control cholesterol by preventing the break up of fats within the blood vessels.

Scientists are currently debating the trial results of this potent anti-oxidant. Among the various theories debated is that carotenoids, including lycopene, may be able to help the body's cells communicate with each other.

Scientists have known for some time that where there is a lack of inter-cell communication, there is the potential for developing diseases such as cancer. There is evidence that lycopene plays a beneficial role in human health by preventing chronic diseases. However; there are more studies planned for the future.

How arteries can become blocked over time

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US death per 100,000 per population from CVDs

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US Deaths per 100,000 Population by Sex and Ethnicity

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Growing evidence that Lycopene rich diet may be beneficial in chronic conditions

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Tomatoes, New Hope For Stopping Heart Disese

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Lycopene, naturally occurring anti-oxidant found in tomatoes and other red fruits and vegetables

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Best Lycopene Foods For Preventing Heart Disease

Foods
Lycopene content per 100g
Quantity
Tomatoes
(cooked) 3041ug
Per cup (240g). One cup of raw cherry tomatoes provides 3834ug of lycopene. One cup of raw, chopped tomatoes provides 4631ug of lycopene
Watermelon
4532ug
Per cup diced (152g) = 6889ug
Papaya
1828ug
Per cup, pieces (145g) = 2651ug
Pink grapefruit
1135ug
Per cup, sections (230g) =2611ug. Per half (128g) = 1453ug
Chilled Tomato Sauce
12819ug
Per cup, (273g) = 34996ug
Pink Guavas
5204ug
Per cup (165g) = 8587ug
Sweet red peppers
Cooked, 484ug
Per cup chopped, (106g) = 513ug
Asparagus
Cooked 30ug
Per 1/2 cup (90g) = 27ug
Red Cabbage
20ug
Per cup, chopped, (89g) = 18ug
Mango
3ug
Per cup, pieces (165g) = 5ug
Carrots
1ug
Per cup, chopped (128g) = 1.3ug
Sun dried tomatoes
45902ug
918ug, per piece (2g)
Tomato puree
21754ug
Per cup (250g) = 54385ug
Dried herbs and spices i.e (Basil)
393ug
per 1 teaspoon (1g) = 4ug
Tomato Soup
10920ug
Per 1/2 cup, (121g) =13213 (121g). Per can (303g) =33088ug
Canned Tomatoes
2767ug
Per cup, (240g) = 6641ug
Baked Beans
511ug
Per cup (254g) = 1298ug
Rose Hip
6800ug
Per ounce (28g) = 1904ug
Some research suggests, that eating tomato products rather than taking a supplement, is the best way of achieving the health benefits attributed to tomatoes.
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Bon Appetit

Gazpacho, Cold Tomato Soup.
Gazpacho, Cold Tomato Soup. | Source

Do You Suffer from Cardiovascular disease

Would you consider taking the new Lycopene pill

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36 comments

tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Nell, who would have though it, is right. I must say, although I love fresh tomatoes, I'm not too keen on the soup, but if it's as good as the research implies, I'll force it down if I have to, but it would have to be home made of course. :)

Nell, I do appreciate you stopping by, take care and my very best to you.


Nell Rose profile image

Nell Rose 2 years ago from England

Hi Jo, who would have thought tomato soup? I always think that soup is made up of everything else apart from tomatoes! lol! I did see something about this the other day, but all your info is much more detailed, so thank you for letting us know, how amazing, that little tomato!


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Torrilynn, a pleasure to see you. The way I see it,, If my hubs help people to make good choices in regards to their health, it is well worth the effort. Thank you so much for stopping by and for the kind comment.

My best to you.


torrilynn profile image

torrilynn 2 years ago

thanks for this useful hub. I love when hubs are helping others to live a healthier and better lifestyle.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Frank, How lovely to see you! Thanks for taking a look at this, I like doing these hubs, I always learn something new.

Appreciate the support. Take care and my best to you.


Frank Atanacio profile image

Frank Atanacio 2 years ago from Shelton

toobusiness you always put out important hubs.. i do read and love reading the healthy ones.. thank you for reminding us of our health with these types of hub...:)


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Hi Genna, sorry about the history but with good insight into the condition, which I know you already have, you can manage most of the risk factors to even things a bit. I'm glad this was useful, thank you for the vote and share, much appreciated. My best to you.


Genna East profile image

Genna East 2 years ago from Massachusetts, USA

Hi Jo…

As someone whose family has a history of heart problems, I read this superb hub with great interest. I am always on the lookout for dietary and supplemental aids in hopes staving off what may be “inevitable,” given the genetic predisposition of heart disease. I can’t thank you enough for this article! Voted up and shared. :-)


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Hi Devika, always a pleasure!

I like to pick tomatoes off the vine and still warm from the sun also, the people of the Mediterranean have kept their secret well for a long time, but now we can all eat healthy. I hope the new research will confirm the benefits of the tomato pill, the potential for health can be far reaching.

I hope all is well, take care and my best to you.


DDE profile image

DDE 2 years ago from Dubrovnik, Croatia

I like tomatoes and when ripe I pick right from the beautiful plants. Eating properly does make one feel great. I enjoyed reading and learning so much more about a unique pill. Take care.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Flourish, my sentiments exactly, it's more practical to take the pill, this way we know that we're getting the optimal dose that is also easy to digest. We can still top-up by eating the raw fruits, baked beans, soups, tomato juice and our favourite tomato or Mediterranean dishes. I appreciate you stopping by, my best to you.


FlourishAnyway profile image

FlourishAnyway 2 years ago from USA

No matter how much someone likes tomatoes (and I don't like them fresh, only in things like sauces), you can't deny the tidbit that one pill equals eating three kg of fresh ones. Wow! I'll take the pill over the real thing this time. Great hub on something that potentially affects us all.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

MsDora, if the tomato pill does half of what it is supposed to do, it would still be worth it. Eating smart, is a good way to go, but there are times when we need a little extra help. The process of atherosclerosis, starts in childhood then it is all downhill, unless we find ways to put on the brakes. Maybe this pill is the answer.

It's always a pleasure to see you, take care and my best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Patsybell, it is a pretty cool photo, a saw it and couldn't resist it, but I hope you also found the hub useful. :) Thank you so much for taking the time to read and comment, I very much appreciated it. Take care and my best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Pamela, I'm so sorry to learn about the heart problem, sometime there's just no real explanation. On the positive side, a few years ago you would most probably needed open heart surgery and a coronary artery bypass graft, they've come a long way, percutaneous angioplasty is so much safer. Science is moving in the right direction, we're getting there. I've just found the Ateronon supplement on amazon. I've placed the amazon link just above this comment capsule. I didn't think to search for the brand name before publishing the hub because the pill had only recently entered the market, but you can buy it from amazon, it's a brave new world:)

Thank you so much for the visit and comment, good luck with the supplement, take care and my very best to you.


MsDora profile image

MsDora 2 years ago from The Caribbean

The tomato pill seems like the new wonder drug for heart patients. Good to see something that works effectively. I also appreciate you listing the foods that supply lycopene. We may not need the pill if we eat smart. Thank you for this very good presentation.


Patsybell profile image

Patsybell 2 years ago from zone 6a, SEMO

Well, you had be at the cool tomato photo.Voted up, U, I, tweet.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Blueheron, autumn olive berries could be a good alternative to tomatoes, I'll have to look it up, but thank you for this valuable addition and for taking the time, much appreciated.

My best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Hi John, yes, it's always exciting when something like this comes along. Drugs like statins have made a huge difference, and continues to save lives, I hope this pill will do the same. I love eating tomatoes, but I'd be setting up home in loo if I attempted to munch through 3kg of the stuff. As always, much appreciated, take care and my best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Ruby, those statistics are pretty scary, parents have to start educating their children early, get in with the healthy options before they discover Mc Donald's and Pizza Hut. I do eat a lot of fruits and vegetables, but my weakness is chocolates. I'll have to substitute my box of Swiss chocolates for tomatoes, not quite the same some how.:)

Always a pleasure to see you. My best.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

DreamMeg, 3kg would make a lovely soup or tomato juice, but I must say, I wouldn't want to be the one to try eating 200 tomatoes to put it to the test.:)

It is still early days for the lycopene pilI but I hope it will prove to be the answer for all those people with CVDs. Thank you for taking the time to read and for the very insightful comment, much appreciated. Take care and my best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Shanmarie, thank you for stopping by, good to see you. High blood pressure is a risk factor, but a manageable one, I hope you are keeping it under control. If you don't want to take the supplement, try some of the other food products on the list, many are also good sources of lycopene. Take care, and my best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Hi Jimmylesaint, you're certainly right about genetics, although where possible, it's good to know the familial history, it is only part of the equation. With growing awareness of how we can best improve our health, the determination to live as long as possible, and advances in science, the statistic should continue to decrease. As much as I love tomatoes, 200 would play havoc with the digestion. :)

Thank you for stopping by and for the insightful comment, much appreciated.

My best to you.


Pamela99 profile image

Pamela99 2 years ago from United States

This pill sounds very interesting and I wonder if it is available in the U.S. A little over a year ago I had a mild heart attach and had two stents put in my heart. I have no disease in any other vessels of my heart, but I think genetics played a big role. I never smoked, I am not obese, etc. I hope they continue to do more long term research on this pill. Fortunately, I do like tomatoes and eat them frequently, but not at the quantity you mentioned.

Very information and interesting article. Up, useful and shared.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Faith, it's always a good to share, especially new information that may improve our health. I certainly need all the help I can get at this point in my life. :) I hope the pill is everything it's made out to be, we desperately need something to help reduce the burden of CVDs throughout the world. I hope the result of your stress test was OK. I walk the dog daily, but I'll have to start increasing the distance now that the weather is improving. As always, thank you for the visit, the great comment and the share, a real pleasure to see you, take care and my best to you.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Hi Bill, if you're not a fan of the tomato, the pill may well be the answer. However, you can still get a good proportion of lycopene in tomato soups, by cooking with the paste or drinking tomato juice. If you really don't like the stuff, then you may as well try the pill. :)

Genetics do play a part, but you can always improve the odds in your favour by doing what I'm sure you are already doing. Take care and my best to you.


blueheron profile image

blueheron 2 years ago from Odessa, MO

Thanks for the wonderful information on lycopene!

Another really good source of lycopene is autumn olive berries--which taste somewhat like tomatoes, but often a bit more tannic. The berries have 14-18 times the lycopene of raw tomatoes. Attempts have been made to cultivate this kind of undesirable tree (it's very invasive) and popularize the fruit as a health food. The berries taste pretty good, though not great. They are kind of a fruit in search of a cuisine. They make a good jam, and can be turned into a faux "tomato sauce"--but one that doesn't taste just right.


Jodah profile image

Jodah 2 years ago from Queensland Australia

Very interesting hub Jo. It is always good to hear about the new medical breakthroughs and medicines becoming available. I would also prefer natural tomato products but it would be impossible to eat enough lycopene to get the amount you do from the pills. Voted up.


tobusiness profile image

tobusiness 2 years ago from Bedfordshire, U.K Author

Jackie, I love tomatoes, I often eat them as I would any other fruits, they taste so much better when you grow your own, no chemicals poisoning. I'm glad you found the information useful. Always good to see you, my best as always.


always exploring profile image

always exploring 2 years ago from Southern Illinois

Bring on the tomatoes. I love them! The statistics are alarming about obesity, so many children are obese. I must work on including more vegies in my diet. Thank you, great research. Well done...


DreamerMeg profile image

DreamerMeg 2 years ago from Northern Ireland

We love tomatoes but I don't think that I could possibly reach a rate of 200 tomatoes or 3kg of them a day! At the moment, I would prefer to keep eating lovely fresh ripe tomatoes on the vine from local growers but you never know, maybe a bit more research will push me towards taking the pill! Very interesting and thought provoking hub.


shanmarie profile image

shanmarie 2 years ago from Texas

Very interesting. Heart disease runs in my family and I already have high blood pressure. Still, I think I would rather just eat tomatoes. I do that quite often anyway. I'm always skeptical of taking supplements and pills for anything.


jimmylesaint profile image

jimmylesaint 2 years ago from Metropolis of Life

Genetics play a small part in disease billybuc. The external environment switches genes on and off at its' leisure. I'm not a fan of tomatoes either but recently chopped them up, added onions(sweetens it) and a bit of garlic and a splash of extra virgin Olive oil. Delicious!

I think the pill they intend to make is like eating 200 tomatoes.

Great Hub excellent details and informative


Faith Reaper profile image

Faith Reaper 2 years ago from southern USA

Hi Jo,

Thank you for sharing all of this useful information here, especially on the new tomato pill, how exciting and interesting. You have opened my eyes as to areas in my life that I need to address as far as improved diet. I love tomatoes and know they are so rich in anti-oxidants. I just had to have a Nuclear Stress Test after the regular stress test, so, we will see. My dad had heart disease and all of the other bad stuff, so I need to be mindful of such and make strides to change for the better. Glad to know that just walking each day is better than having to go for the hard core workouts at the gym : ) ...

I have heard of the Mediterranean diet and how wonderful it is, and we do use olive oil in our diet.

Up ++++ tweeting, pinning, googling and sharing

Blessings for a lovely Sunday


billybuc profile image

billybuc 2 years ago from Olympia, WA

Great information, Jo! I admit, I don't like tomatoes, but I would take a tomato pill. This is such important information. Being adopted, I have no idea about my genetics, so I have to pay close attention to these risk factors. Thank you for this, and blessings to you always.

bill


Jackie Lynnley profile image

Jackie Lynnley 2 years ago from The Beautiful South

I would rather eat the tomato products but you never know when they may not be so readily available or trustworthy for this. I do have tomatoes largely in my diet loving them so much. Have been on a search for a local seller lately. So far my heart is in great shape; perhaps having tomatoes a big part of my diet is why! Thank you for this valuable information.

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