Chaparral (Creosote) Extract Extends Longevity of Mice

Scientists at the University of Michigan, led by Richard Miller, have found that an extract from a common American shrub, called chaparral or creosote (Larrea tridentata), has extended the life of male mice in laboratory tests.

The bush's longevity power is believed to be attributed to a natural anti-inflammatory in its extract, called nordihydroguaiaretic acid (NDGA). Chaparral has a tradition of being a healing herb among Native American tribes. Earlier research at the University of California, San Francisco, demonstrated that NDGA has anti-cancer properties.

While scientists caution that humans should not self-administer NDGA because not much is known about its effect on humans (and, apparently, a few things are harmless to mice but deadly to us), the findings are significant enough to be shared with the scientific community for peer review in the journal Aging Cell.

However, chaparral, in the form of tea, is readily available. Native Americans drank chaparral tea to treat colds, menstrual cramps, skin disorders and minor wounds, chicken pox, and diarrhea.

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Comments 5 comments

Maddie Ruud profile image

Maddie Ruud 9 years ago from Oakland, CA

Interesting. I can honestly say I'd never heard of it. I'll have to look into it.


Lyricallor profile image

Lyricallor 9 years ago from Croydon

I wonder how it would do to treat arthritis...thanks for sharing!


livelonger profile image

livelonger 9 years ago from San Francisco Author

Not sure. It is an anti-inflammatory, though.


Vic 9 years ago

This is great news. I wonder if it worked as well on female mice and if not, why.


cgull8m profile image

cgull8m 9 years ago from North Carolina

Hope they do more studies and find out whether it can be successfully applied for humans also.

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