Certain medical disorders, tnvrstar, can cause physical coldness. Anemia is an example of a lowered red cell count in the blood, that causes feeling cold.
Autoimmune diseases, which are various and often overlapping, sometimes include Raynaud's syndrome. Raynauds causes extremely cold extremities (turning nails and skin bluish to white) resulting from vascular abnormalities seen in some autoimmune sufferers. Wearing gloves and heavy socks is necessary in extreme cases to avoid the eventual loss of digits. Autoimmune diseases such as Crohns or colitis with frequent diarrhea can dehydrate sufferers with resultant lowered body temperature due to fluid loss, which can cause feeling cold. Hashimotos disease, an autoimmune disorder of the thyroid, has this symptom, as well as hypothroidism and hypopituitarism.
Similarly, any disorder that impacts the vascular system, which circulates the blood, can cause coldness; such as heart disease.
Often, in cases of eating disorders such as bulemia and anorexia, its victims will feel cold. Extreme weight loss, in the absense of an eating disorder, when caused by illness or aging, can cause an individual to feel very cold. And, any physical condition that lessens the ability for mobility will render patients cold.