Fibromyalgia and Gender
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Gender Differential in Fibromyalgia
Fibromyalgia, or more precisely the fibromyalgia syndrome, has become over the years the subject of much attention. This syndrome is a perfect model of pain and all its complexities. Never a week goes by without the publication of more research about the effects of different new treatments.
What the research is also revealing answers the questions posed in the title. Reseach into pain medecine has revealed that male and female sex hormones have very specific differences when it comes to the mechanics of pain and the experience of pain. Male hormones have a higher anti-nociceptive effect, which modulates pain, than female hormones. This could explain why women who have fibromyalgia seem to experience more pain than men who have also been diagnosed. That is that women have a lower pain threshold for this type of pain than men whose pain threshold is improved by pain inhibitors present in androgens – naturally occuring male steroid hormones.
This identification of hormonal influence on pain in fibromyalgia (and other conditions) has led to the research of treatments using neurosteroids which have sedative, relaxing effect. They are steroids which are synthesized directly in the nervous system and play a decisive role in the transmission and integration of sensory messages responsible for painful sensations. However, use of neurosteroids can inhibit the effect of anti-depressants. As some fibromylagia sufferers may also be prescribed anti-depressant medicine it is important to discuss this with the doctor.
Because of this counter indicative marker between neurosteroids and anti-depressants neurosteroids are not yet available as a pain treatment.
It is important to remember th fibromyalgia is a very complex syndrome which affects both the peripheral and central mechanisms of pain. The treatments for fibromyalgia are multiple and complementary. The belief that drug treatment alone will relieve this syndrome is an illusion. It is important for suffers to do some regular physical activity suited to their age and condition and irrespective of gender. Physical exercis has a central analgesic effect that may be even more effective than that of drugs.
All About Fibromyalgia
- Fibromyalgia
Fibromyalgia is a syndrome with many symptoms. The three primary symptoms are chronic pain, fatigue and sleep disturbances. There are numerous other associated ailments which are usually referred to as... - Fibromyalgia Demystified
Fibromyalgia - this article demystifies this often misunderstood syndrome. - Prospering Over Fibromyalgia
I will start by saying that the truth is that every patient with Fibromyalgia is different. No two of us experience the exact same symptoms, levels of pain, levels of fatigue, or physical challenges in the same way. - Fibromyalgia and Gender
Fibromyalgia, or more precisely the fibromyalgia syndrome, has become over the years the subject of much attention. This syndrome is a perfect model of pain and all its complexities. Never a week goes by... - The Fibromyalgia Research Blog
The latest in fibromyalgia research, news, and clinical trials. - Fibromyalgia and Sexuality
People with fibromyalgia find soon get use to the fact that their daily activities can be disrupted the many and varied unpleasant symptoms of this syndrome. Certain symptoms such as pain, fatigue and...
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Comments
Thanks for this. I must have Wee One give it a read. I know there are some Dr.s that don't even believe in this syndrome, a male thing I suppose and pure idiocy too. I sure hope the best for you for I know how it can totally disable women. Don't know of any men that are affilcted by it, my Family Physician thought I may have it, but not so. Good luck dear
An important topic indeed. My husband has FM and one of my friends brothers also. Definately not a womans condition. I wish there were more clinical studies and research on FM - it is an awful affliction. Newest studies are suggesting that it is probably neurological - but more research is needed for sure! I hope I live to see the day a cure or successful treatment is available.
Thank you for bringing more attention and understanding to Fibromyalgia.
Your right without exercise activity, like walking, the meds are worthless. Let me give you a unique perspective.
I'm 1 in 10 men out of every woman that have been diagnosed with fibromyalgia. I'm a rarity since this is not common in men. I was diagnosed about 2 months ago after experiencing all tendor points since 2004. I could never figure out why my body began to hurt everyday, every joint for without reason. This was so frustrating. If it wasn't for my own research through the years and medical self-advocating to rule out everything from Parkinsons, lupus, cancer, MS, immune, nervous, etc., any less of a person may have just given up where the depression left them in worse shape. Fortunately I was to persistent for that.
My fibro came about per "doc's" characterizations of fibro secondary to military injuries while serving 22 years in two branches of service. I like to refer to this as massive internal damage that has cooked my pain receptors and rerouted super sensitivity back to my brain. Regardless my CNS with regard to pain tolerance is toast.
In my case, any form of anti-depressant for pain drug really messes up my head. I can't take them. So instead, I boost brain chems through daily walking. This helps alot. However, when I quite moving... Let the pain train begin.
I'm on a pain management program that does not include anti-depressants. In my opinion, those with previous neck injuries, or whole body injuries... Don't bank on anti-depressants wholly. If you feel crummy using them, get off of them! Find something else!
I've tried about everything the doc's recommended to include every specialist in the book, natural cures, etc., I call "poppycock" for those that had an amazing cure benefit... Most likely they experienced an acute characteristic fibro experience that was not pure fibro! True fibromyalgia is very difficult to diagnos.
I have to admit a rheumatologist-immune specialist is the closest to determining whether you have it or not and hold medical opinion weight over all other doc specialists, especially a primary physician.
The best thing one can do is take up a walking program, stretching, swimming, light weight reps to isolate and work indirectly around heavy pain trigger point(s) which vary in intensity on any one day. Oh yah, don't forget nutrition, but I won't go into this. This is my specialty to include exercise and pain management.
If you get a chance I'd appreciate you visiting my profile and a follow if you like my topics. I'm now following you. I think we have some similar interests.
You are correct, there is no cure, there is no known "exact" cause. Although science is working to fund studies around, previous injuries patients, depression, immune, IBS & most likely a whole aray of cause/origin possibilities.
I think those that try to profit off this selling snake oil should be ashammed of themselves. Because those that say their fibro diagnosed... And magically it disappears after using supplements, natural cures, etc., I'm highly skeptical of their intentions and for that matter... Who diagnosed them with Fibro? A primary physician. If so, that does not hold a whole lot of weight because any doc can state in the medical transcripts (characteristic of fibromyalgia... or like).
Good Write, and good point!
Fibromyalgia in the News
- Managing fibromyalgia: it isn't only about medsKIVI Boise20 hours ago
Treating fibromyalgia isn't just about medications. Education about the disease and a carefully planned exercise program also help manage the pain and improve the quality of life.
- Managing fibromyalgia: it isn't only about medsKMIR 6 Palm Springs20 hours ago
Fibromyalgia is a syndrome that causes widespread pain, fatigue and problems thinking. If you have it, you may also suffer from digestive problems and mood swings. The exact cause of fibromyalgia is not known. Because of this, there is no one single treatment that works.
- Is chronic pain ruining your relationship?CNN2 days ago
Athena Champneys, 37, has been in near-constant pain since 2003, when she was diagnosed with fibromyalgia, a chronic condition characterized by widespread pain and tenderness. Her husband hasn't always been 100 percent sympathetic, however.
- Some like it rawPark Hills Daily Journal4 hours ago
COLUMBIA, Mo. (AP) — Inside the Cambridge Clubhouse, food is the main topic of conversation. It’s Sunday night, and it’s time to eat.
- Health calendarHonolulu Advertiser4 hours ago
"FREE FOR LIFE" TOBACCO CESSATION PROGRAM, four-session treatment, 6-8 p.m., Jan. 4, 8, 11 and 15, Unity Church of Hawai'i, Diamond Head, room 201; $100; registration, 735-4436.












Julie-Ann Amos says:
10 months ago
Useful hub and I like the images!