Ovarian Cancer
74Ovarian Cancer Symptoms
CNN - Ovarian Cancer
Ovarian cancer
Stimulate the body's defenses to fight ovarian cancer
Two percent of all newborn girls in the United States are at risk for ovarian cancer
Up to 30,000 U.S. women will be diagnosed with ovarian cancer this
year. In 2006, 15,000 to 16,000 women are likely to die from this
silent murderer. Ovarian cancer is the leading cause of death among 5
women, and is responsible for about five percent of all cancer deaths.
Chances are, your doctor may have diagnosed. That is often the case. A
recent British study found 60 percent of all UK general practitioners
had diagnosed their patients. Three quarters of British doctors
surveyed incorrectly assumed that symptoms only occurred in the late
stages of ovarian cancer. Based on this information should not be
surprising that Britain has one of the lowest survival rates for
ovarian cancer in the Western world - from 6,800 cases diagnosed each
year, more than 4,600 die.
A similar discovery was made by
researchers at the University of California, which announced last year,
"Four in 10 women with ovarian cancer have symptoms that tell their
doctors about at least four months - and while a year - before to be
diagnosed. According to their study of almost 2,000 women with ovarian
cancer, researchers found physicians:
• First ordered
abdominal imaging or perform gastrointestinal procedures instead of
more appropriate and pelvic imaging or CA-125 (a blood test that can
detect ovarian cancer).
• Only 25 percent of patients who
reported symptoms of ovarian cancer four or more months before
diagnosis were given pelvic imaging or CA-125 had blood tests.
Patients with initial symptoms are often misdiagnosed. Abdominal
imaging or diagnostic gastrointestinal studies are less likely to
detect ovarian cancer. According to the website of the American Cancer
Society, "The most common symptom is back pain, followed by fatigue,
bloating, constipation, abdominal pain and urinary urgency. These
symptoms tend to occur frequently and become more severe with time.
Most women with ovarian cancer have at least two of these symptoms. "
At the time a woman reaches the fourth stage of ovarian cancer,
first-line treatment is often carboplatin, paclitaxel and cisplatin
chemotherapy specific for ovarian cancer. In the first stage, the
cancer is inside one or both ovaries. In the second stage, the cancer
has spread to the fallopian tubes or other pelvic tissues, such as the
bladder or rectum. When the cancer has spread beyond the pelvic area in
the abdominal cavity, especially when tumor growths are more than two
inches in the lining of the abdomen, then ovarian cancer has reached
stage three. The fourth and final stage of ovarian cancer is reached
when the cancer has spread to other body organs such as liver or lungs.
If detected early, survival rates can be as high as 90
percent. Detected in the advanced stage, the survival rate falls to
between 30 and 40 per cent. Several imaging tests such as computed
tomography (CT), magnetic resonance imaging (MRI) and ultrasound
studies can confirm whether a pelvic mass is present. Laparoscopy can
help a doctor look at the ovaries and other pelvic tissues in order to
plan a surgical procedure, or to stage ovarian cancer. A biopsy, or
sampling of tissue, could confirm whether there is cancer in her pelvic
area, and help determine how advanced. An elevated CA-125 blood test
usually indicates that the cancer has progressed to an advanced stage.
About 50 percent of patients with ovarian cancer are already at an
advanced stage when a correct diagnosis is made. Only 10 to 14 percent
of women with advanced cancer are likely to survive more than five
years.
Evaluation of treatments
While research shows
drinking black (or green) or herbal tea supplement ginkgo biloba may be
useful as a preventive measure or to reduce the risk, women had few
options when their cancer has moved to the stage advanced. In the first
stage, a woman is facing surgical removal of the tumor, and possibly
one or both ovaries, to increase their chances of survival. Beyond
that, their choice is chemotherapy.
A major problem with
chemotherapy side effects. The most advanced cancer, may be weaker,
reducing the potential for survival. Survival rates have not changed
much over the past fifteen years. Chemotherapy can increase survival
time by up to 50 percent. However, the quality of life suffers. Side
effects and increased toxicity that accompanies chemotherapy, how one
moves to reduce the prolonged survival time.
Some minor side
effects of paclitaxel, which was denounced by Medline Plus and may
include nausea, vomiting, loss of appetite, altered taste, thinned or
brittle hair, pain in the joints of the arms or legs, changes in the
Nail color and / or tingling in hands or feet. The most serious side
effects may include blisters in the mouth or fatigue. Some side effects
may include unusual bleeding or bruising alarming, dizziness, shortness
of breath, severe fatigue, chest pain or difficulty swallowing. The
most common side effect of paclitaxel is a decrease of blood cells.
Carboplatin has its own list of side effects. You can reduce the
production of platelets, which may interfere with the ability of blood
to clot. You can become anemic, tired or breathless. Nausea, vomiting,
loss of appetite and a general feeling of weakness are common with this
chemotherapeutic agent.
Comedians like Gilda Radner and Madeline Kahn, Oscar-winning actress
like Loretta Young and Sandy Dennis, the wife of the singers Laura Nyro
and Dinah Shore, actor Pierce Brosnan, Cassandra Harris, actress
Jessica Tandy, former Connecticut Gov. Ella Grasso, and the wife of
Martin Luther King, Coretta Scott King died of ovarian cancer. It's not
just celebrities, politicians or movie stars, she was diagnosed with
ovarian cancer. One in 55 women U.S. is at risk of ovarian cancer. The
American Cancer Society estimates about 22,000 new cases of ovarian
cancer is diagnosed. Over 16,000 women will die because the symptoms
are often subtle, and your doctor does not recognize the symptoms early
enough. Is the leading cause of death from gynecological malignancies
and the fifth leading cause of cancer death among women.
Silent
and undetected, this cancer often spreads beyond the ovary or ovaries
in the abdominal cavity, or the final stage, in other body organs like
the liver or lungs. Family physicians often fail to properly diagnose
"the murderer quiet" until it's too late. Last August, researchers at
the University of California Davis, said 40 percent of women said their
doctors about their symptoms for as long as a year before they were
correctly diagnosed. A UK survey found 75 percent of family physicians
think that symptoms are present during advanced stages of cancer. At
the time, women are diagnosed with ovarian cancer, 40 to 50 percent of
patients are in the advanced stage, where there is little hope for
survival.
Less than half of women diagnosed with ovarian
cancer will live five years. About 10 to 14 percent live beyond five
years after diagnosis. Your choices have been limited, mainly
restricted to variations of chemotherapy drugs or a new form of drug
delivery. The general public is often unaware of the adverse effects
experienced by patients with ovarian cancer during chemotherapy. In
mid-March, the Food and Drug Administration U.S. criticizes the safety
profile of Eli Lilly's Gemzar for ovarian cancer patients, saying the
increased survival of 2.8 months seen in studies of patients taking the
drug was not sufficient to offset increased toxicity of the treatment
included anemia, neutropenia (a blood disorder) and thrombocytopenia
(low platelets in the blood). Currently used first-line treatment for
patients with ovarian cancer include cisplatin, with adverse events,
such as nerves, kidneys and / or damage to hearing, Carboplatin (side
effects: damage to nerves in the arms and / or legs, joint pain and /
or thrombocytopenia), paclitaxel (neurotoxicity), or melphalan, with
side effects including irreversible failure of the bone marrow, bone
marrow suppression).
The woman developed symptoms of ovarian
cancer is facing the first surgery, then chemotherapy. Recent press
advertising and extensive new development in the treatment of ovarian
cancer, intra-abdominal or intraperitoneal chemotherapy, is just that
more chemotherapy. The "belly bath" as it has been dubbed by some
television journalists, has been much praised, because treatment can
prolong life for some 16 months more than "regular" chemotherapy. The
results were published in the prestigious New England Journal of
Medicine in December 2005. Most news reports failed to mention that
only 40 percent of women treated with a belly bath were able to
complete all six cycles. Why? The therapy is based on infusions of
paclitaxel and cisplatin (see side effects in the previous paragraph).
According to Dr. Robert Edwards, director of research at Magee-Women's
Gynecologic Cancer in Pittsburgh, "Many women do not feel well enough
to work for the duration of the intra-abdominal (treatment)." Some
patients, like Cindy Pakalnis Marshall (Pennsylvania) treatments have
called "exhausting."
The unresolved problem of chemotherapy is
to reduce the "quality of life." While some life extension has been
demonstrated, the patient's life deteriorates. Many patients struggle
with the balance of the loss in quality of life with the rigors of
therapy. Researchers are actively pursuing new directions that could
one day provide new hope for patients with ovarian cancer. The
University of Minnesota research study has suggested the use of
thalidomide, which is used in combination with chemotherapy as a
potential means of increasing the chance of remission. Minnesota cancer
researcher Dr. Levi Downs explained, "prevents the tumor from making
new blood vessels. Without new blood vessels, the tumor can not be
adequately feed the new cells, so cancer can not grow. "The randomized
trial was small with only 65 patients (only 28 had the thalidomide),
and certainly more tests are needed.
Ovarian cancer is a silent murderer one of the greatest threats to
women's health. The American Cancer Society says about 20,180 U.S.
women will be diagnosed with ovarian cancer this year alone. Each woman
faces a risk of 1:57 risk of getting ovarian cancer during their
lifetime.
The symptoms of ovarian cancer are not noticeable
until the cancer spreads, criticism, explaining that thousands of women
die from this terrible disease each year. Although ovarian cancer can
be treated, in most cases are detected late, leading to complications
and death in patients with ovarian cancer.
Given that to date
there is no safe and effective way to diagnose or detect ovarian cancer
in its early stages, specialists, research groups and cancer advocacy
groups and government organizations are doing all the research ovarian
cancer that may finally shed light on the gray areas of this deadly
disease. Some organizations provide scholarships for those willing and
interested in carrying out research on ovarian cancer.
Among
the most important organizations that promote awareness of ovarian
cancer is the Ovarian Cancer National Alliance. Formed in 1997 by seven
groups of ovarian cancer defense that joined forces to strengthen
efforts to promote education of ovarian cancer.
Research teams
ovarian cancer research on several areas including ovarian cancer
symptoms (in both the first and the last stage), stages, risk factors,
prevention, risk reduction, and treatment with objective of raising
awareness of this cancer. Knowledge of these areas may be old
protection against this cancer.
However, apart from the fact
that there are many information gaps that still need to be filled,
ovarian cancer research is carried out in response to the high rate of
cancer mortality. In the United States, ovarian cancer is the fifth
among gynecologic cancers than women out on the edge of death. Over 50%
of all women diagnosed with the disease are to die within five years,
research shows. It is this fact that the research groups of ovarian
cancer are exerting their best effort to discover hidden truths about
ovarian cancer.
Most ovarian cancer research reveals that
women with ovarian cancer exhibit the following symptoms: persistent
and perplexing gastrointestinal upset, nausea, gastrointestinal
disturbances, distention or bloating, pain in the pelvic and abdominal
area, fatigue, frequent bleeding urinating, and abnormal during the
postmenopausal stage.
Recent research on ovarian cancer
conducted by the University of California, shows that over one third of
women diagnosed with ovarian cancer have shown symptoms of at least
four months before they have been diagnosed with cancer, what is a good
chance that ovarian cancer can be diagnosed earlier.
The
researchers explained that the reason the cancer is detected when it is
in its advanced state is that doctors do not perform tests that could
diagnose cancer immediately. Generally, doctors have the image of
patients undergoing abdominal and certain gastrointestinal procedures,
they say you're not as effective in diagnosing this disease.
Other research of ovarian cancer are concerned about improving the
treatment of ovarian cancer and the prevention of this disease. Many
clinical studies are conducted to analyze carefully the potential of a
drug in the prevention of women at high risk of developing ovarian
cancer and in treating those in the early and late stages of cancer.
Ovarian cancer, tea, and an ounce of prevention
Ovarian cancer and hysterectomies - Being informed about your options
A
hysterectomy is not often a procedure to be performed urgently, except
in the case of cancer. Therefore, a woman considering the procedure
should take time to investigate all options, including other possible
treatments. Now there are new treatments for diseases that previously
would have required a hysterectomy. She advises women to a hysterectomy
for a noncancerous condition before being offered more conservative
treatments may be appropriate to seek a second opinion.
In
deciding whether to undergo a hysterectomy can be a difficult and
emotional process. Being informed about the procedure, women can
confidently discuss available options, concerns and wishes with your
doctor and make a decision that is right for them.
If, too,
have been questioning the need for surgery of fibroids, prolapse,
incontinence or "celebrations" of repairs, was reassuring to know that
you have every right to do so. The decision to undergo surgery of any
kind is often difficult, so it is often useful to explore other
alternatives before going ahead. Women, especially at the time of
menopause, all too often is advisable to undergo major gynecological
surgery for minor conditions that can be significantly improved with
natural alternatives
Every 10 minutes, 12 hysterectomies are
performed in the United States. That's over 600,000 per year, of which
only 10% are due to cancer. This surgery most often not diagnosed and
corrected the problem rather than the results of the trials again. And,
says Dr. Stanley West, author of the joke of the hysterectomy, nine out
of ten hysterectomies are unnecessary.
We have to ask? How
have these surgeries in the quality of life of women? "Nowhere in the
gynecological literature did the study versus the number of women for
whom sex has become painful or impossible. Nowhere were studies to
track the number of marriages or who were not seriously affected as a
result of these postoperative complications or alcoholism or drug
addiction resulting from chronic debilitating pain.
Women who
have been hysterectomized experience a lot of negative side effects
such as chronic pain and fatigue, depression and pain during sex. These
are only a fraction of the long list of unwanted symptoms reported by
women after surgery.
So, if you choose, or have already
decided, that surgery is not an option, you may ask, "What now?" I have
asked myself this same question. But I'll tell you, no quick fix. As
women we must understand that our bodies to look after them in a
positive way.
The more I think about it the hottest issue
that I feel for informing women before making this important decision.
Prevention is the key and the hormonal balance is the answer.
In most of whom are encouraged to remove her uterus is likely to suffer
from excess estrogen that is also explained by Dr. John Lee.
Balancing hormones involves working on a few fronts through simple strategies.
1. Evaluate your hormones with a saliva test - determine what is
happening in your body - ask your self the question - Are you estrogen
dominant? Using a saliva test to find the answer.
2. Optimize
your diet by reducing insulin levels. More than 2 / 3 of Americans are
overweight. This balances the extra weight increases insulin causing
estrogen dominance increased. EAT 40/30/30
3. If the saliva test shows the need to use a natural progesterone cream in the process of rebalancing your hormonal system
4. Exercise to reduce excess estrogen and to eliminate toxins
5. Drink more water
6. Supplement with wisdom to our program balancing hormone fiber, indoles, EFA, multi - fruit and essence veggies, calcium
Abdominal Chemo increases ovarian cancer survival rate
A large trial shows that giving chemotherapy directly into the stomach
and in a vein, can improve survival of women with advanced ovarian
cancer by about sixteen months. The results of the study, which appears
in this week's edition of the New England Journal of Medicine, led the
NCI to issue a statement of support for physicians to use this plan of
attack for appropriate patients.
Why is reigmine new
treatment is so important? Ovarian cancer is the fourth biggest reason
for cancer deaths in women, affecting more than 22,000 women and
killing more than 16,000 in 2005. Although this disease is treatable
when it was super early, almost all cases go unnoticed until they have
spread beyond the ovaries. Because many patients with ovarian cancer is
diagnosed at a later stage, it is essential to find ways to improve
treatments for the disease progressed further.
What is known
about ovarian cancer? virtually all women with advanced ovarian cancer
receiving chemotherapy after surgery to remove the tumor. That
chemotherapy is usually given in a vein and moves through the
bloodstream to reach tumor cells in the stomach. Doctors have also
experimented with the delivery of chemotherapy directly into the
abdomen through a catheter, a system called intraperitoneal (IP)
chemotherapy. Eight clinical trials of this approach have been made,
and most showed an increase in IP chemotherapy. But this technique is
not widely carried, according to the study's author, Deborah Armstrong,
MD.
"There has been a prejudice against IP therapy in ovarian
cancer because it is an old idea, that requires skill and experience
for the surgery and chemotherapy, and is more complicated than IV
chemotherapy," said Armstrong, who is medical oncologist and associate
professor at the John Hopkins Kimmel Cancer Center in Baltimore.
How did this study: Women with ovarian cancer stage III were randomly
assigned to get either standard chemotherapy into a vein (210 women),
or a combination of chemotherapy into a vein and IP chemotherapy (205
women). The woman had already had surgery that successfully removed all
or most tumors, none had remaining tumors were larger than 1 cm in
diameter. All women were treated with the same drugs, cisplatin and
paclitaxel. Six cycles of chemotherapy were planned for both groups.
What was found? Women who had long operated IP chemotherapy without
their cancer returning, and have lived more generally. Women who had
received traditional chemotherapy into a vein survived 4 years after
treatment, while those who received chemotherapy in the stomach,
stomach and a vein from an average of almost 5 ½ years after treatment.
That improvement is "one of the largest benefits ever observed
for a new therapy in gynecologic oncology," based on data from Stephen
A. Cannistra, MD, author of an editorial published with the study. He
is a professor at Harvard Medical School and managing director of the
division of gynecologic oncology at Beth Israel Deaconess Medical
Center in Boston.
However, the IP treatment was much more
difficult in patients. Women who had this treatment was much more
terrible or life-threatening side effects, including low white blood
cell count, infection, fatigue and anxiety. Many were the side effects
associated with the catheters to be inserted into the stomach to
deliver the chemotherapy. These problems are so severe that less than
half of women appointed to undergo IP chemotherapy completed all six
cycles of treatment designed. This makes the progress of survival than
a good complementary offering remarkable, Cannistra compound.
Women who received IP therapy also reported worse caliber of life
during and after treatment. For a year away, however, both groups
described similar quality of life.
Ovarian Cancer in the News
- Boehringer Ingelheim Initiates First Phase III Clinical Trial In Ovarian CancerMedical News Today13 hours ago
Boehringer Ingelheim announced today the initiation of a new phase III clinical trial to evaluate one of its two late-stage oncology pipeline compounds for the treatment of patients with advanced ovarian cancer. The clinical study, called LUME-Ovar-1 trial, investigates the compound BIBF 1120, a novel oral anti-angiogenic agent , for its efficacy and safety as first-line treatment in combination ...
- Research Suggests Link Between Infertility, Low Egg Reserve, And Breast/Ovarian Cancer Gene (BRCA1)redOrbit2 days ago
New findings may help explain why women who carry a mutated BRCA1 gene have greater rates of infertility as well as a greater risk for breast and ovarian cancer
- Catching Ovarian Cancer EarlyFOX 4 News Dallas - Fort Worth2 days ago
A new pre-screening test for ovarian cancer may be available by the end of next year.
- Ovarian Cancer in the Yahoo! Directory
Yahoo! reviewed these sites and found them related to Ovarian Cancer - Ovarian Cancer
Overview of ovarian cancer and the tests used to evaluate women who may have the disease - Ovarian Cancer: eMedicine Obstetrics and Gynecology
Overview: Ovarian cancer is the most common cause of cancer death from gynecologic tumors in the United States. Early disease causes minimal, nonspecific, or no symptoms. Therefore, most patients are diagnosed in an advanced stage. Overall, prognosis - Ovarian Epithelial Cancer Treatment - National Cancer Institute
Expert-reviewed information summary about the treatment of ovarian epithelial cancer. - Ovarian Cancer << Frequently Asked Questions << womenshealth.gov
- Ovarian Cancer Home Page - National Cancer Institute
Information about ovarian cancer treatment, prevention, genetics, causes, screening, clinical trials, research and statistics from the National Cancer Institute. - Ovarian cancer - Wikipedia, the free encyclopedia
- Ovarian Cancer: MedlinePlus
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enlightenedpsych2 says:
3 months ago
This was one of your longer better hubs that I am more familiar with: I had an ovarian cyst (benign not cancerous or malignant as it is called) which could of become cancerous had I the marker in my DNA for it. Thankfully I do not. It burst in 2006 and what I discovered in research since being diagnosed with it over five years ago, I found my diet and the early use of birth control was the reason it manifested.
I urge young women to practise abstinence for as long as they can and NOT use any of the synthetic birth control treatment options available to them AND make sure they don't choose to skip necessary toxic-cleansing menstrual cycles. A womans body does need one every month--it is just common sense !
Thank you again for posting a very important hub that needs to be read by many many women, young and old. I will come back and add something else. In the mean time, I enjoy your writing.
sharing the light,
miss erica hidvegi, the Enlightenment Advisor