Star Trek: Enterprise (titled Enterprise prior to season three) is a science fiction television program set in the Star Trek universe created by Gene Roddenberry.

The series, which follows the adventures of the pre-Federation Enterprise, premiered on September 26, 2001. Enterprise's pilot episode, "Broken Bow", takes place in 2151: 10 years before the Federation's founding, and about halfway between the 21st century events shown in the movie Star Trek: First Contact and the original Star Trek.

Because of low ratings, UPN cancelled Enterprise on February 2, 2005, but allowed the series to complete its fourth season; the final episode aired on May 13, 2005. After a run of four seasons and 98 episodes, it was the first Star Trek series since the original Star Trek to have been canceled by its network rather than finished by its producers.

• the first Star Trek series to be produced in widescreen

• the first Star Trek series to be broadcast in HDTV

• the first Star Trek series to be filmed on digital video (season 4)

• the first Star Trek series since Star Trek: The Next Generation to debut at the start of a TV season rather than at mid-season

• the first Star Trek series to have a theme song with song lyrics that were used (the theme to Star Trek: The Original Series originally had lyrics, but they were never used)

• the first Star Trek series to feature podcast commentary.

• the first Star Trek series (indeed, the first science fiction television or movie production in history) to use actual video footage taken on another planet (the Sojourner rover approaching the Yogi Rock, taken by the Mars Pathfinder lander and used in the opening credits).

• the first contemporary Star Trek Series (developed in the last 20 years), to be cancelled due to poor ratings.