quit smoking medicine which has worked !

What is it?

This quit smoking medicine contains bupropion hydrochloride, is intended for people who want to quit smoking
The Zyban quit smoking medicine is in reality an antidepressant drug. In the USA, it's sanctioned for consumption in the treatment of clinical depression, as seasonal major affective disorder and for treating smoking cessation. The generic names put-upon for the drug are Bupropion and Amfebutamone.

The trade name, whilst distributed as an antidepressant drug in the U.S., is Wellbutrin. In the UK, it's exclusively sanctioned for use in folks who would like to quit smoking, not for the treatment of depression or additional disorders. It has no legal condition in other nations.

How?

The precise mechanisms of the mode of action of bupropion are not fully clarified. We know that this is at levels of the mediators of brain cells, such as norepinephrine and dopamine. The Zyban reduces the urge to smoke, and affects the pleasant feeling ,which is caused by smoking and also treats the symptoms of the lack of nicotine. Also limits the weight gain that often occurs after leaving the cigarettes.

For what kind of people?

It is aimed at smokers who have decided to quit smoking and cigarettes. This medication requires a medical, as well as a plan to quit cigarettes. Is particularly recommended for people who have problem to nicotinic substitutes, who have had failures with them or who have a history of depression. It is the physician who judges what is the medication assistance best suited to their needs.

What is their effectiveness?

The success rate in a year for Zyban is between 23 and 30%. By way of comparison, certain combinations of nicotinic substitutes (patches, gum or patches and nasal spray) with a comparable efficacy between 18 and 27% rate of abstinence.

Bupropion and other anti-depressants to quit the cigarettes

* See the summary of an article by the Cochrane Collaboration

Contra-indication Zyban

There are absolute contra-indications to Zyban which are imperative to respect: Hypersensitivity to the product, epilepsy, brain tumor, severe behavioral eating disorder (bulimia nervosa, anorexia mental), alcohol dependence, and sedative drugs, certain medications (MAOI inhivitadores of the mono-amino-oxidase). There are also situations where it is possible to use Zyban with caution often a reduced dose if the physician believes that the advantages of Zyban outweigh the risks: kidney failure, liver failure, alcoholism, head injury, lack of sleep, making certain medications (antidepressants, neuroleptics, theophylline, tramadol, antimalarials, quinolones, corticosteroids by mouth or injection) Only your doctor can prescribe Zyban. Tell the good of all the medicines you take, so you can adjust your treatment.

Side Effects of Zyban

* Insomnia in 25 to 65% of cases
* Dry mouth
* Restlessness, anxiety, agitation
* Depression
* Earthquakes
* Headache
* Dizziness
* Tachycardia, chest pain
* Abdominal pain, vomiting, constipation
* Rash
* Urticaria angioedema
* Very rarely, seizures (risk 1 in 1000)

Important: Many of these side effects can be attributed to smoking.

Treatment

In accordance with your doctor taking Zyban should start between 7 and 14 days before the date you set to quit, time to allow the substance to develop its effects.

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During 6 days Zyban take 1 tablet of 150 mg in the morning ..
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From the 7th day of treatment should take 2 tablets per day, and another one to get up to half a day, this for 6 weeks. We have to respect a period of 8 hours between the two doses of Zyban. Never take medicine at night (insomnia) if you forget to take some better wait for the next morning. In total, followed by a treatment between 7 and 9 weeks.
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In case of prolonged and significant side effects, do not quit treatment without first consulting with your physician, may reduce the dose to 1 tablet daily, thus reducing side effects and effectiveness is almost equal to quit.

Zyban, pregnancy and lactation

As with many drugs there is little data on the effects of Zyban in humans. There are no known toxic effect of Zyban on the development of the baby during pregnancy, especially malformation. Same whether it is better to use it outside of pregnancy, it is possible to administer during pregnancy. Talk with your gynecologist and find the best solution. We must consider the toxicity of cigarettes during pregnancy is shown to increase the risk of abortion and birth prematuros.Si is planning a pregnancy, with approximately one week for the elimination of Zyban once quitped taking. Since the active ingredient of Zyban passes into breast milk, breastfeeding is discouraged during his administration.

Making a combined possible?

The association with the use of Zyban substitutes nicotinic possible. But greater efficiency is not proven scientifically.

Price

For 7 weeks of treatment, or 92 tablets, we must be 285 Swiss francs, or between 130 and 142 euros depending on the country. This treatment is equivalent to a daily consumption of 26 cigarettes, according to the price of the package. In Switzerland this drug can not be obtained without a prescription and is restricted to those over 18 years. Not reimbursed by basic health insurance, but is sometimes caught in a cargo insurance.

A controversial drug Zyban

Regularly in the media information on Zyban arouse controversy and public concerns. Facing the different information and controversies have appeared lately in the media about this product, here is the opinion of Dr. JP Humair:

The recent announcement of the deadly dangers of Zyban in United Kingdom, is a typical example of distortion of information to health so often by the media. These indeed have turned the information "57 deaths during or after the taking of Zyban in more information with a hook 57 deaths Zyban.
He recovered to the source of information and based on available data about the Zyban, dare I say the following details:

* The 57 deaths are nothing more than notifications of deaths of people taking or have taken recently at the agency Zyban British Medicines Control.
* These notifications are a normal process of controlling all the drugs and the numbers are always higher after the introduction of a new drug.
* These notices are the subject of an investigation that have not shown any relationship by the time the cause and effect between these deaths and Zyban.
* Most of those killed were a disease to explain his death, a large number due to smoking.
* Like people who quit smoking (with or without Ziban) have developed a new disease caused by cigarettes as the risk decreases only gradually in a few years.
* All studies carried out so far have shown no difference in the number of deaths among smokers and users of Zyban those taking a placebo
* This medicine is used to quit smoking in the United States and in Canada since at least 5 years ago and has never been proved the existence of deaths due to Zyban, this is also the case for Wellbutrin which contains the same substance at doses higher for the treatment of depression.
If these deaths were attributed to Zyban (which is not currently the case) the risk is negligible (57/4000.000, or 0.014%) and compared with the enormous risk of death due to cigarettes that is 50%!.

In summary, the media is more concerned with selling their information to the public health, fear of getting into the population. On the other hand we must seriously doubt the impartiality of the media about smoking because they are financially very dependent on the industry cigarettes where they also stick their ads.