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When and if you don't enjoy it any longer.
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If you like it, write forever.
If something inside urges you keep up.
Providing that the brain works, never, unless there is a physical problem that can't be overcome. Writers can no more stop writing than actors can stop acting, than painters can stop painting...
When you need to. Ask yourself that question and see what the answer is.
When you get tired. People are likely to make mistakes when they are tired. Rest, and then start again.
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