Yes from shared experiences and personal experience. The first is with when a friend returned from vacation. The seal where the hose between the pipe and toilet inlet leaked. That toilet was upstairs above the kitchen. When they returned they walked into the home discovering a kitchen wall completed saturated with a few inches of water on the floor. Uggg!!
The bottom line is the kitchen had to be deconstructed and remodeled with an emphasis on mold and its control. A wall in the hallway leading into the foyer also had to be at the lower half. Appliances along that wall were flooded and required replacement because of the impact with the electrical and electronics.
Thankfully there was insurance, but there was a cost with time, inconvenience, and misery. Seals wear out and do leak. It is good to bring up this point with your experience and this one too.