Chrons Disease Symptoms Help and Facts
About Chrons Disease
Chrons disease is a type of inflammatory bowel disease (IBD) and can affect any part of the gastrointestinal tract from mouth to anus it has no cure and not alot is known about what causes Chrons Disease except for that it has Genetic links
Causes of Chrons Disease
As mentioned earlier no-one is really sure what causes Chrons disease, there seems to be a genetic link and some environmental factors have also been sugested as causes or factors that increase the chances of getting Chrons Disease.
If you eat food that is high in sweet, fatty or refined foods this may increase your chances of developing Chrons disease, this could also explain why so few people in the undeveloped world develop the disease.
People who smoke also increase the risk of getting chrons disease (crohn's disease)
What does Chrons disease do to the intestines?
Chrons disease in the early stages can cause small, shallow, crater-like areas called erosions on the inner surface of the bowel which are pretty scattered. These erosions are officially called aphthous ulcers.
Over time, these aphthous ulcers develope to become deeper and larger, ultimately becoming true ulcers which means that they are deeper than erosions this causes scarring which makes the bowel stiffer.
As Chrons disease progresses over time, the bowel narrows, and can actually become blocked (obstructed). These deep ulcers can also make holes in the wall of your bowel, the problem with this is that bacteria which is in the bowel can spread and infect nearby organs and the abdomen.
As Chrons disease narrows the small intestine and blocks it obviously this also stops the flow of contents through your intestines. This can happen suddenly if poorly digested food plugs the narrow area. When this happens, your food, fluid and gas from the stomach cannot pass into the colon. The symptoms of a blockage include severe abdominal cramps, vometing, nausea and abdominal distention.
What are Fistulas?
Fistulas and Chrons Disease
The ulcers that can form walls of the small intestine and the colon and can tunnel into an adjacent organ. This is called a fistula.
If a fistula developes between the intestine and the bladder this is called an enteric-vesicular fistula which can cause a urinary tract infection and sometimes you will pass gass and faeces when you urinate.
If a fistula forms between the intestine and the skin this is called a enteric-cutaneous fistula, this can cause pus and mucous to come out of a small painful opening on the skin on your abdomen.
A fistula that grows between the colon and the vagina is called a colonic-vaginal fistula. This usually means that gas and feces twill come through the vagina.
A fistula from the intestines to the anus is called an anal fistula and oftem means mucous and pus will come out from the fistula's opening around the anus.
Links to other Chrons Disease Sites
- Living with Chrons Disease Symptoms
A Blog about living with Chrons disease, medical advancements and advice
- Chrons Disease page on Wikipedia
Very comprehensive page on Chrons Disease including the definition, Crohn's disease Symptoms and treatments
- About Chrons Disease
A webpage helping people who suffer from Chrons Disease, contains facts about Chrons aswell as advice and help.
- Chrons Disease on Medicine.net
Very factual and informative article on Chrons disease
Ancestor Of Chrons Disease Pathogen comes from an Indian Bug?
Seyed E. Hasnain and his team from the Institute of Life Sciences at the University of Hyderabad in India has discovered that a mycobacterial organism Mycobacterium indicus pranii (MIP) could possibly be one of the earliest ancestors of a branch of mycobacterial pathogens.
This branch of pathogens are known as 'generalist' bacteria and can infect anything from insects to humans. One of the most deadly diseases on the planet, TB is caused by a member of this Mycobacterial family of pathogens.
What has this got to do with Chrons Disease you may ask?
The reasearsh also seems to suggest a link to it's close associate Mycobacterium avium paratuberculosis (MAP) which is the agent of Chrons disease. It was also found that the MIP and the MAP bacilli initially inhabited water bodies and only infected marine organisms which were eaten by fish. It finally arrived on soil through bird-droppings. (I guess from fish eating birds?)
This study provides an important step forward in understanding the role of non-pathogenic and saprophytic mycobacteria in triggering innate immune responses and hopefuilly is another step forward in the fight against against Chrons disease.
Please Note: This article has been adapted from material provided by the Public Library of Science.