Hello Mighty Mom,
Thanks for the question. Clickbank Pirate has been the best program for me. It's the easiest program on the market today because they supply everything for you. Plus, I'm making money from it. That's always good.
Maverick Money Makers is not a bad program. A little bit more difficult to use, but not much.
Global Domain International (GDI) is a program I would stay away from. Now, I haven't tried it myself, but what I've heard about it is that it's difficult to make money.
So, in my opinion, Clickbank Pirate is my favorite affiliate Marketing program. I hope I answered your question.