How to Make a Natural Cure for Multiple Sclerosis

Noni fruit on a palm

Brace up for multiple sclerosis on the rise because of pollution and lifestyle


You can make your own supplement to prevent and treat multiple sclerosis, a disease involving nerves. If you are not confident in doing it yourself, you can ask the help of a pharmacist.

An example of a supplement is raw garlic that is munched to treat hypertension. A supplement is usually natural in contrast to a drug, like aspirin, that is formulated and made by a pharmaceutical laboratory.

Onset of multiple sclerosis

Multiple sclerosis will not attack like an epidemic because it is not caused by a microbe. But it is on the rise because it is caused by free radicals and reactive oxygen species (definitions below) that our body produce and we get from the environment, food and lifestyle like smoking and drinking wine. Jonas Salk, after the success of the killed-virus polio vaccine he and his team developed, conducted medical research on multiple sclerosis (Kluger, J. Splendid Solution, Jonas Salk and the Conquest of Polio. 2004). It alarmed him because multiple sclerosis afflicts the nerve cells just as the polio bug attacks the nerves in the spinal cord and medulla oblongata that result in paralysis or death. It afflicts all ages.

“In a study at the Mayo Clinic in Rochester, Minnesota, the medium age at onset was reported to be 37.2 years (range 16.7 to 65.3) for men, 35.4 years (range of 16.7 to 65.3) overall…. Approximately 10% to 15% of our patients are diagnosed before the age of 20 (mostly in their late teens, although pediatric MS is being more often recognized nowadays), whereas about 5% of patients are diagnosed above the age of 49 years” (Despande, R. et al. “The Natural History of Multiple Sclerosis.” Advances in Neurology. 2006. 8:1-4).

Nature of multiple sclerosis

Multiple sclerosis (damage to nerve cell) contributes to decrease in thinking ability. “Multiple sclerosis is a chronic neurological disease of the central nervous system (CNS) characterized by immune-mediated myelin loss with variable degrees of axonal injury” (Morales, Y. et al. “The Pathology of Multiple Sclerosis: Evidence for Heterogeneity.” Advances in Neurology. 2006.8:28).

The central nervous system consists of brain and spinal cord. Axon and dendrite are types of morphological processes of nerve cells. Axon conducts impulses.

An axon is like an electric wire that conducts electricity, not of one piece though but cut up into several units, with a gap between two units called synapse. Mineral ions (like calcium) serve as bridge across synapses. Myelin wraps axons like an insulator protecting wire. In holistic medicine, free radicals damage the wire and insulator so that messages hardly pass through, or could not at all.

Symptoms of multiple sclerosis are double vision, limb stiffness, fatigue, pain, depression, tremor, impaired cognition (attention, memory, perception, reasoning), seizure, acute relapses, vertigo, dizziness, weakness and more.

Preparations

Things to consider in making a supplement are: (1) elements should be natural, therefore unpatented, (2) the source should be safe, not poisonous, (3) gadgets to use should be safe, free of microbes, (4) the place or laboratory where to work must be aseptic, free of microbes, (5) the person who makes the concoction must be aseptic and knowledgeable or at least must have had a laboratory experience, for example, in school, (6) heat is not applied, heat destroys enzymes, (7) the concoction must be tested for bacteria during and after manufacture, (8) trial on a test animal, (9) only a small amount is taken for the first trial on man, (10) the shelf life of concoction must be ascertained, how long does it keep unspoiled and still potent.

If you use fruit, test it for safety; test it for presence of cadmium, lead, arsenic and mercury. Use a fruit that had been tested beforehand by laboratories or whose properties are published in reliable sources. There are methods and chemicals for use to make your laboratory, juice maker, utensils, gadgets, containers, clothing, shoes, hair, and gloves aseptic.

These preparations are easy which is why I make this recommendation for multiple sclerosis. I could make similar recommendations for other disease but these will be for other Hubs.

Framework

Some necessary clarifications to make about “immune-mediated.” Morales and colleagues used a framework that postulates that the immune system is “confused” in attacking the cause of disease (like microbe) and the healthy cells. Such confusion is explained by Dr. Dean Ornish as follows:

“Sometimes the body gets confused and thinks part of itself are not-self. As a result, the body begins to attack itself. The resulting illnesses, called autoimmune diseases, can affect any part of the body. Rheumatic arthritis is an example of an autoimmune disease in which the body begins to attack the joint” (Ornish, D., MD. Dr. Dean Ornish’s Program for Reversing Heart Disease. 1996:239).

Another way of looking at “immune-mediated” is explained as follows: “Antibodies produced by the body in response to the streptococci proceed to attack part of the heart, which they misidentify as streptococci” (Clayman, C. B., MD. editor. Your Heart. 1989:90).

The framework we are using in this Hub is the free radical theories of disease. Multiple sclerosis is caused by free radicals that attack the myelin and axon. Both myelin and axon are disabled and are lost if severely attacked. The nature and symptoms of multiple sclerosis are the same whether the framework is germ theory or free radical theories of disease. The differences lie on the belief on causes, development of disease and on treatment.

Treatment

Let’s qualify what is meant by “treatment.” Suppose a person is suffering from hypertension. During normal times his blood pressure is 130/80. When he is provoked to anger his blood pressure shoots up to 160/90 which is considered as hypertension. He takes a tranquilizer, say, losartan, and his blood pressure gets down to 130/80. The next time that he is provoked to anger his blood pressure shoots up to 150/80. Again, he takes losartan. His hypertension does not go away. Losartan is a treatment. The National Heart, Lung, and Blood Institute issued in May 2003 that the normal blood pressure is 119/79 (Sotile, W.M., Ph.D. with R. Cantor-Cooke. Thriving with Heart Disease. 2003:25).

Cure is another matter; we will not discuss it now.

Scientific basis

There is a scientific basis in the recommendation of making your own supplement to prevent and treat multiple sclerosis (MS).

MS is treated with glatiramer acetate (GA) consisting of “random sequences of four naturally occurring amino acids: L-glutamic acid, L-lysine, L-alanine, and L-tyrosine in racemic form (molar ratio of 1.4:3.4:4.2:1.0). The copolymer was first synthesized in 1967 by Drs. Arnon and colleagues at the Weizmann Institute of Science in an attempt to simulate some of the then-known physicochemical properties of myelin basic protein (MBP) to induce and then dissect experimental allergic encephalomyelitis....

“The immunopharmacology of GA in humans remains incompletely understood, but substantial preclinical and clinical data support immunomodulatory and neuroprotective effects that may contribute to the activity of the drug....” (Wolinsky, J. S. "The Use of Glatiramer Acetate in the Treatment of Multiple Sclerosis." Advances in Neurology. 2006. 8:274).

Random sequence means that elements are mixed in no particular order. We see L (meaning left) in elements of glatiramer. We also see L in glucose but usually see D (meaning right). L glucose and D glucose are chemically identical (like two sides of a mirror); they only differ in how they rotate light, potency, and absorption. In vitamin E, there is a DL form called racemic form (Di Cyan, E. Ph.D. Vitamin E & Aging. 1977:21). The active form is DL-alpha tocopherol but DL is usually dropped. In glatiramer, the L is mentioned but since the quotation qualified the mixture of elements as “racemic form,” both L and D forms are present. Thus, the glutamic acid, lysine, alanine, and tyrosine are all in DL form. However, the L form is probably better absorbed for multiple sclerosis thus more emphasized.

The elements are found in nature, like fruits. The fruit of noni (Morinda citrifolia, Linn.) a medium-height tree growing in Haiti and Pacific rim countries like the Philippines contains a lot of elements, 64 in all (Elkins, R. The Noni Revolution. 2000). Noni fruit contains elements that go into the making of glatiramer acetate supplement. You may use other fruits or vegetables that contain the necessary elements for the MS supplement.

To be effective, your supplement should have the right ratio of elements. On this aspect the pharmacist will be of help. Noni juice must be analyzed for percentage of elements it contains to suit the required ratio

Ensure safety

Noni fruit is certified safe: lead content (mg/L less than 0.0100); arsenic content (mg/L less than 0.00100); cadmium content (mg/L less than 0.0030; mercury content (mg/L less than 0.0001). Its content of these metals are negligible to be considered as toxic.The toxicity of noni fruit and juice had been studied:

“Data from clinical studies, toxicity tests, and chemical test have substantiated the use of this juice as a safe food. More detailed examination of the few recently reported cases of adverse health effects reveals that these were likely due to factors other than noni fruit” (Wang Mian-Ying, Brett J. West, C. Jarake Jensen, Diane Nowicki, Su Chen, Afak Palu, Gary Anderson. Acta Pharmacol Sin. 2002 Dec. 23(2):1127-1141).

The process of manufacture may be a company secret; it is patentable. Elements are not patented because they are natural.

You may use a juice maker on ripe noni fruit, picked from the tree. You can experiment on the degree of ripeness. Include the peel and seeds. The juice will be creamy. After two or three days, it will turn watery, dark brown and will smell like red wine.

Although noni is certified safe, you may want to test your supplement on a cat or dog for toxicity. Noni juice is already being applied as a veterinary supplement.

If you surf the internet you will find plenty of branded noni products in the market. I am not sure if these can be used in making a supplement for multiple sclerosis.

Prevention

Your MS supplement may protect you as primary prevention, that is, it prevents MS from taking a toehold on you. It will help control the population of free radicals. Your body makes a lot of free radicals and reactive oxygen species (ROS) that are derived from free radicals and act like free radicals do. For example, the metabolism of sugar (glucose) to produce energy produces free radicals as by-products. One free radical produced by the body is superoxide that by itself inflicts damage and initiates production of ROS like hydrogen peroxide, hydroxyl, alkoxy radical. Reaction of free radicals and ROS with cholesterol produce a bad cholesterol that contribute to plaque in heart arteries that may result in angina, heart attack, heart failure or irregular heart beat.

A free radical or a ROS has at least one unpaired electron that is unstable. To attain stability the unpaired electron grabs another electron from a molecule of a tissue or organ. The victim of grabbing is injured; injury results in multiple sclerosis, tumor, cancer, and other free radical diseases.

There should be a balance between the population of free radicals and ROS on the one hand, and on the other, the population of supplements like antioxidants and built-in enzyme antioxidants of the body like superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione synthase. A balance prevents oxidative stress. An imbalance in favor of free radicals and ROS results in disease.

Free radicals abound in the environment: pollution, ozone, smoke, radiation.

Your supplement designed for multiple sclerosis will protect you against other free radical and ROS diseases as well.

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