No I don't think so. We are likely see a return of the "Moderate Republican" whose primary focus will be on improving the economy and keeping our shores safe.
Preaching to the choir about social issues especially those that are intended to limit individual freedom or equality are not going to lead to very many national election victories.
It's been reported that 85% of youth (our future) support "marriage equality". You don't need a crystal ball to know that a country which espouses (separation of church and state) is not going to allow religious beliefs to dictate what people do in their private lives. Marriage equality is now viewed as a "civil rights" issue.
Immigration reform with a path to citizenship is coming. Republicans lost 72% of the Latino vote to Democrats in the last presidential election.
Planned Parenthood and Pro-choice are here to stay. Any attacks against them is seen as an attack on women or efforts to control their bodies.
Odds are when more phases of The Affordable Healthcare Act aka Obamacare become a part of the norm... repealing it would be similar to trying to get rid of social security and Medicaid. They are both sacred cows!
Any party that alienates the youth vote, minority vote, senior vote, and women's vote is not going win a lot of national elections.
Having said that it would not be the first time a political party re-invented itself. Remember it was the Republican party that pushed for abolishing slavery. Over 80% of Republicans in congress voted to pass the Civil Rights Act of 1964 during a period where Southern Democrats were aligned with the KKK.