Pick up lines have never worked in my experience but they have made me laugh a lot in the past, I remember some of my friends trying out different lines when i was young and the results where never good.
I wrote a hub on the subject a few months ago http://hubpages.com/relationships/pick-up-lines-li...
it gives a different way of dealing with the subject you may find interesting.
My dad gave me some good advice when I was younger he said, it doesn't matter what you look like or where you're from, a girl will always be attracted to you if you can make her laugh.
This is probably the best piece of advice he ever gave me or maybe it was buy a house when your 18 I'm not sure he might of just wanted me out of his house haha