@Kelly Pittman: Since you've asked, I'll go ahead and tell you where I stand.
I've hit a lot of personal bumps in the road myself. When I was a child and even during my college years, I thought I knew exactly what that something great was. I had these ideas of getting things to happen for me without trouble: marrying with a family on the way, making a fortune with a job I love, and being a popular with everyone I meet.
Well, none of those things have happened, so I've struggled over the years to figure out what exactly I'm meant to do that would be great for me. In fact, when I failed with goals that I set for myself (goals I thought I was destined to do), I became very cynical and lost my self confidence. It's gotten better recently, but I still struggle with it, so I'm the 100% cheerful optimist I used to be.
I'd honestly say it would have to be my writing where my something great lies. It's encouraged me to try to step out into the world again and see what's really happening out there...and made me think about what I can on my part to help the people in it. On top of that, my writing gets the messages I think are important for people to know about out in the world and at the same time I get people writing back to me telling me their thoughts and dreams.
And I think in a lot of ways we go through that somehow...getting one idea of what we're good at doing, but realizing that's it exactly what we're meant to do. It could be we're better at something else and that something else is really a testimony to the kind of individual we really are. It takes a lot of stumbles and failures to figure that all out and it can get frustrating, but the struggles can help build an incredible person within you if you keep your mind open to all possible choices and paths.
I hope this answers your question. And thank you to everyone for your insightful answers!