The answer is 42 as Victoria stated.
The real problem is what is the question to the ultimate answer?
While this might sound trite on the surface it isn't so simple.
When someone asks you if you believe in god, your first question should be what is a god?
I've yet to hear any real answer that fulfills the requirements, hence I can't believe in the existence of a god.
Likewise, asking the meaning of life has no single answer as life is very different for each of us. Ask instead what does your life mean to you?
When you say the universe perhaps a better question is whether there is only this universe or are there more lying beyond? There could be as many universes as there are stars and we simply don't know it, or at least can't prove it.
Science and religion look inward to the center of the universe to try and figure out where it began. But are they looking in the wrong direction?
Everything? I doubt that we will ever know everything let alone what it is.
If we are truly living we should be learning something new every day.
So the answer is 42; however I should point out that if you were to know both the question and the answer there would be no further point to life and you would cease to exist,,, a bummer for sure.
I highly recommend the book (The Hitchhikers Guide to the Galaxy) but don't forget to read between the lines.