The origin of blue eyes: a common ancestor

Recent research shows that people with blue eyes have a single common ancestor. A team from the University of Copenhagen has managed to trace a genetic mutation that makes Logar had 6,000 to 10,000 years and that is causing the color of all blue-eyed people in today's world. 

"Originally, we all had brown eyes," says Professor Eiberg from the Department of Cellular and Molecular Medicine. "But a genetic mutation affecting the OCA2 gene in our chromosomes proved to be a switch which literally turned off the ability to produce brown eyes." The OCA2 gene codes for the protein called P, which is involved in the production of melanin, the pigment that gives color to hair, skin and eyes. The "switch" which is located in a gene adjacent to OCA2 does not turn off the gene entirely but limits its action to reduce the production of melanin in the iris with the effect of diluting the color brown eyes blue. Therefore, the effect on OCA2 is very specific. If the OCA2 gene had been completely destroyed or turned off, human beings have no melanin in their hair, eyes or skin. This condition is known as albinism. 

The other eye colors 


Variation in eye color from brown to green can be explained by the amount of melanin in the iris, but blue-eyed people only have a small degree of variation in the melanin in their eyes. "From this we can conclude that all people with blue eyes are linked to the same ancestor," says Professor Eiberg "We all have inherited the same change in the exact same spot in their DNA.". Brown-eyed people, by contrast, have considerable individual variation in the area of DNA that controls melanin production. 

The mutation from brown to blue eyes is neither positive nor negative. It is one of several mutations such as hair color, baldness, moles or beauty spots, it does not increase or reduce the ability of survival of man. As Professor Eiberg says, "simply shows that nature is constantly mixing the human genome, creating a genetic cocktail of human chromosomes and trying different changes as it does."

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Comments 6 comments

Wayne Brown profile image

Wayne Brown 5 years ago from Texas

Interesting...how do you account for three children in a family...one with blue eyes, two with green? How did that one ancestor evade the other two kids? WB


Nell Rose profile image

Nell Rose 5 years ago from England

Hi, fascinating stuff! I have blue eyes therefore I am related too! I always wanted to know the genetics behind it, cheers nell


debrabritt 5 years ago

Still did not tell us who that person was now did it?


debrabritt 5 years ago

Makes no sense what is Loger? that whole sentence is Crap.


Sandra 5 years ago

Logar is a province of Afghanistan so the ancestor they are speaking of is Persian Descendants


Grant 23 months ago

Afganistan? How does that relate with that until about 200 years ago 90% or more of blue eyed population lived in Scandinavia?

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