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Feline Infectious Peritonitis (FIP): An Insidious Disease With A High Mortality Rate.

Updated on October 29, 2017
Bob Bamberg profile image

Bob has been in the pet supply business and writing about pets, livestock and wildlife in a career that spans three decades.


Arguably The Ultimate Cat Conundrum

Right now there’s no known cure for it and there’s not even a simple diagnostic test for it. Feline infectious peritonitis, FIP for short, is a progressive viral disease that, unfortunately, is almost always fatal.

Oh, it starts out innocently enough. It’s caused by certain strains of the feline coronavirus, most of which don’t even cause disease or, if they do, may cause fairly mild intestinal or respiratory symptoms.

But sometimes, at some point, either the virus mutates or the cat’s immune system malfunctions and the disease develops into FIP.

In a cruel twist of fate, the disease turns the cat’s own defenses against it as white blood cells become infected with the virus.

White blood cells, which normally protect against invaders that can do harm, now partner with the virus and carry it throughout the body.

These cells collect in the abdomen, and sometimes in the kidney or brain, and ignite a severe inflammatory reaction in the tissues of those organs.

Once symptoms develop, the disease gets worse and worse over ensuing weeks until the cat finally succumbs.

Animals, including pets that you think would know better, will instinctively hide symptoms of illness or injury because, in their world, if you’re vulnerable, you’ll get beaten up or eaten. Domestication hasn’t particularly changed that.

And cats seem to be particularly adept at it until the situation they’re hiding reaches the crisis stage.

Therefore, even though the disease has been simmering for a long time, it may seem to you to have developed almost overnight.

There are two forms of FIP; the dry form and wet form. Cats exhibiting symptoms of the dry form may become lethargic, lose weight, and have a persistent fever.

These symptoms are more gradual than those of the wet form.

Symptoms of the wet form progress more quickly as the cat becomes pot-bellied due to an accumulation of fluid in the abdomen or, less commonly, in the chest.

If the build up of fluid becomes excessive, the cat may find it hard to breathe normally.This is where the family members' observations become so important.

Since there is no test to confirm the disease at the onset of symptoms, veterinarians presume the diagnosis based on the symptoms that bring the cat to the clinic, a thorough medical history, and a battery of lab tests.

So it may be a good idea to occasionally remind those in the household of the importance of taking note of things as far as the cat is concerned.

Knowing about even subtle changes in the cat's behavior, eating habits, bowel habits, etc.could be helpful to the veterinarian.

So don't discount as unimportant seemingly innocuous things that occur.

The disease is more common in multi-cat environments, but in the general cat population is seen more often in kittens, older cats, cats infected with feline leukemia (FeLV), or cats with compromised immune systems.


FIP can’t be cured yet, so all one can do is support the cat with proper nutrition and good medical care.

Veterinarians can drain accumulated fluid, and provide fluid therapy, blood transfusions, and drugs to hopefully induce a period of remission.

Otherwise, about all you can do to protect your cat is make a conscious effort to maintain the cat's optimal health.

That means providing a high quality diet, being vigilant about litter box and other sanitation issues, determining with your vet what vaccinations should be updated, and getting advice from your vet about a quarantine period for any new cats brought into your home.

There is a vaccine available, but it’s known to have minimal, if any, preventive qualities. You might decide it’s worth a shot, but you should have a “risks vs. benefits” discussion with your vet about it first.

© 2012 Bob Bamberg


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    • Bob Bamberg profile image

      Bob Bamberg 5 years ago from Southeastern Massachusetts

      Thanks for stopping by and commenting, Theophanes. The ordeal you're going through right now is truly a test of courage, which you're passing with flying colors, and it vividly exemplifies the headline of this hub. I and all cat lovers who read this salute you and wish for you the strength to see the ordeal through its conclusion.

      Those of us on the outside looking in are seeing a colony of sick cats that are not dying alone and unloved, but instead are being granted the dignity of passing in the arms of someone who cares for them and will mourn them. I hope you find comfort in knowing how much your labors are appreciated.

      When the last of the colony has passed, and you have the opportunity to reflect upon the events of that period, I'll bet what you think of the most is what great little personalities they were, and will feel privileged to have been chosen to escort them to the Rainbow Bridge.

      As for your conclusion that you doubt you'll ever want cats again; I'll believe that when I see it. God speed, Theophanes.

    • Theophanes profile image

      Theophanes 5 years ago from New England

      I got stuck with an FIP positive colony after I had an animal hoarder live at my house for awhile. I had no idea at the time she was a hoarder but suffice to say she threw my life and the lives of many many cats into terrible despair. I have seven cats left from the ordeal and its very hard to watch them knowing that someday they're just going to succumb and there's not anything you can do about it, no matter what great little personalities they were or how much you loved them. When they die off completely I don't think I ever want cats again. Way too emotional an ordeal.

    • Bob Bamberg profile image

      Bob Bamberg 5 years ago from Southeastern Massachusetts

      Thanks very much for your kind words, Patty, they're very much appreciated. It takes a little effort to research the meanings of the words used in the scientific literature, but it's worth the effort because it helps me to understand things better and enables me to write it so that the rest of us Average Joes can understand it.

      It's so frustrating that we know so much about the disease yet are powerless to prevent or cure it. Maybe someday...

      I salute you for the work you do with feral colonies. You help bring dignity and quality to lives that are pitiful and fraught with danger. It's because of you and your colleagues that cats like Peter live out their days loved and valued. Thank you for that, and thanks for stopping by and commenting. Regards, Bob

    • Pages-By-Patty profile image

      Pages-By-Patty 5 years ago from Midwest

      The most comprehensive article on FIP that I have found. You put it into layman's terms all while outlining the complexity of this dreaded disease. Any one of us who cares for colonies has witnessed the devastation of FIP. Tears are a flowin' as I think of a feral named Peter who passed from this 2 years ago. He was so brave...

      Once again, thanks so much Bob for your animal education. I think you should have DVM after your name!