only if the female is the standard size can you breed the two. rather, i should say SHOULD only breed the two so long as the female is the larger of the two. of course, there is the issue of getting the smaller male to penetrate the female and to stay inside the female during the fertilizing act itself. as you know the head of the penis swells and creates a plug, the plug keeps the penis in place until all the sperm have left the male and impregnated the female. if the female is larger, means the vaginal cavity is also larger, the male may not be able to win the battle of remaining locked for the period of time necessary for fertilizing the female ovum.