How old are each of the rabbits in question, what breed, and what kind of demand is there locally for them? Research ideal breeding ages, especially for the doe. If you don't already have homes lined up, you'll have to make sure that you have sufficient housing for the babies where they can be separated according to gender, and possibly separated into individual cages as they get older. Bucks will often kill each other as they mature if they're kept together too long. Bear in mind that you could be talking about a LOT of babies -- I used to raise rabbits (and have a detailed description of my rabbitry on a couple of hubs) and the litters ranged on average between 7-12 young, but sometimes as much as 16. You'll need a good nesting box and a LARGE cage for the doe, and as stress-free of a place to put her as possible...she will eat the babies if she gets stressed, and many first-time mothers take very little to be pushed into harming or rejecting their young. In other words....if you're just looking for a single litter for kicks or "the experience", you'll probably find that it's not worth the preparation and work that goes into them, especially since in most places the most you can hope to get for a mixed-breed rabbit is about $5-$10, and it takes a LOT more than that to raise them in a home setting. Also be sure to research how you can tell if the doe is ready to breed, because she will likely attack the buck if she's not ready, and rabbits cause serious injury very quickly when they decide to fight.