Knucklebones were the first form of dice and were used from very ancient times for gambling. They were usually taken from the anklebones of sheep and marked on four sides. Proper dice, carved out of bone to give an even, six-sided shape, were used by the ancient Egyptians in about 2000 BC, and also by,the ancient Chinese. Greeks and Romans also enjoyed playing with dice. Knucklebones were never made from human knuckles.