Excellent answer Suramya !
Hope you get the point Cardisa.
To add to the answer of Suramya :
1. If my understanding is correct, what you are trying to do is to create an website and want to earn through it.
2. You want to include Adsense in it.
3. All you have to do is, create some good original content in it, satisfy yourself and add the Adsense code snippet in your site.
4. Adsense will start paying you for any clicks/impressions you get from this site also.
Adsense for content is same, whether you publish from a content platform like HubPages or from your own site.
As Suramya explained, Adsense for Domains is for the parked domains and I guess you dont have to worry about it.