Your profile score is a combination of an average of your hubs, and the amount of time and energy that you spend in the hubpages community. The top hubbers usually spend time answering questions, hubhopping, and participating in forums. These things will all add to your profile score.
To Google, it really does not matter. To the hubpages community, some say yes, and some no. It is a matter of opinion. The ones with 100 profile scores are usually the top hubbers though. I have also seen hubbers whose profile scores were very high and they had not written a single hub.