This depends on the reason you are on HubPages. If you are here to make money, then again it depends on how much you want to make. You could spend time working out what is hot on Google, Twitter and Facebook and write hubs on those topics if you wanted to chase trends. This would only be temporary of course and once trends changed, you would have to write a whole bunch of new ones.
Personally, I think you should write about a subject you are passionate about and let that passion shine through. Interlink your hubs and announce them on Social Media and hopefully "if you build it, they will come".