ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Cell Signalling

Updated on December 14, 2012

Cell signalling is the communication between cells by means of chemicals for co-ordination between cells.

There are three main types of cell signalling:

  1. The receptor acts as an ion channel
  2. The receptor activates a G-protein
  3. The receptor acts as an enzyme

Although there are three types of cell signalling the basics remain the same.

A signal molecule (this could be a hormone) attaches to a receptor molecule in the plasma membrane (a protein or glycoprotein) . If the two have a complimentary shape, (the signal molecule fits the receptor molecule, like a lock and key) this will bring about a response in the cell. Each signal molecule has a specific receptor, this is how the cell decides which reaction or response is appropriate.


The receptor acts as an ion channel

In this method the signal molecule attaches to a receptor in this case a channel protein this changes the shape of the channel opening it and allowing ions into the cell. This brings about a response.

Source

The receptor activates a G-protein

In this the signal molecule attaches to the receptor in the plasma membrane, this activates a G-protein inside the cell. This in turn activates an enzyme which brings about a reaction inside the cell.

The receptor acts as an enzyme

In this third type of cell signalling the receptor is an enzyme in 2 parts. The signal molecule slots into both parts of the receptor, creating one active enzyme. This enzyme brings about a reaction inside the cell.

Comments

    0 of 8192 characters used
    Post Comment

    • loquacious-mare profile imageAUTHOR

      Phoebe 

      5 years ago from Isle of Wight

      Well thank-you for reading it, cell biology is the part of biology that interests me the most!

    • Caleb DRC profile image

      Caleb DRC 

      5 years ago

      TFScientist, This is so absolutely cool. Do you have a hub on this? I have a bunch of questions but I need more information to develop them. For example, is the "signalling cascade within the cell" specifically timed, and if so what determines the timing? "Division of labor" to whom? Specific cells, or molecules? I'm glad they are not unionized--would that ever screw things up. I'll go to your site and check out your hubs.

      Loquacious, Thanks for writing this hub and getting me started on what is going to be a very fascinating study.

    • TFScientist profile image

      Rhys Baker 

      5 years ago from Peterborough, UK

      A conformational change of the G protein causes a signalling cascade within the cell. This will ultimately cause the desired effect, usually utilising division of labor to achieve it. For example, the change may trigger the endocytosis of an extra cellular substance, which will be directed to the Golgi body in a vesicle. The substances will then be transported to the correct area of the cell. It is like morse code signalling, where the movement of the hammer causes a distinct message to be transmitted, which in turn is changed into a physical letter that can be acted upon.

      Of course this is a gross oversimplification. What causes the response is different for each signal and each response. This allows for strict control of response by the cell.

    • loquacious-mare profile imageAUTHOR

      Phoebe 

      5 years ago from Isle of Wight

      I'm not sure, but in some cases the reaction stimulated by the enzyme creates a substance needed.

    • Caleb DRC profile image

      Caleb DRC 

      5 years ago

      Very interesting. I'm curious, do you happen to know what causes the response after communication has been made?

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://hubpages.com/privacy-policy#gdpr

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)