ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

MCQs - Leptospirosis

Updated on September 15, 2015

Leptospirosis - How is it spread?

Water bodies contaminated with rodent urine
Water bodies contaminated with rodent urine

Leptospirosis - Introduction

Leptospirosis is an infectious disease. It is caused by spirochaetes. Farmers who do not use foot wear and who are exposed to contaminated water with rodent urine were the most common patients getting admitted with leptospirosis. Now the trend is changing. Anyone who is exposed to contaminated water and with break in their skin integrity is at risk. This includes people who explore forests and marshy lands and also city dwellers that live in cities with improper drainage system. In Indian cities like Kolkata one small scale rain is enough for water logging. These cities are also not free from rats and rodents. There lies the risk of getting the disease

Which are the two types of leptospirosis?

Icteric and Anicteric

Edematous and Non edematous

Haemorrhagic and non-haemorhagic

None of the above


Answer: Icteric and Anicteric

Which are the signs and symptoms of anicteric leptospirosis?

Flu like symptoms

Nausea and Vomiting



All of the above


Answer: All of the above


Which are the signs and symptoms of icteric leptospirosis?



Renal failure


Involvement of other organ system

All of the above


Answer: All of the above

Which form of leptospirosis is known as Weil’s disease?





Answer: Icteric

Which are the tests done to diagnose leptospirosis?

Culture of leptospires

Microscopic agglutination testing


Renal function studies

Coagulation studies

Liver function studies

CSF analysis

Chest radiography

Biliary tract ultrasonography


All of the above


Answer: All the above

Diagnostic Tests for Leptospirosis

  • Culture of leptospires and Microscopic agglutination testing are the definitive diagnostic tests.
  • Microscopic agglutination testing can be done only in reference laboratories.
  • Other tests are done to check the involvement of other organs.
  • For example, if the liver is involved, the liver function tests may show abnormalities and patient may have jaundice, nausea, vomiting or abdominal discomfort.


Did you know that the icteric form of leptospirosis is known as Weil's disease?

See results

How is leptospirosis transmitted?

Exposure of mucous membranes or abraded skin to the contaminated water

By mosquito bites

By contact with the infected person


Answer: Exposure of mucous membranes or abraded skin to the contaminated water

Which groups of people are at risk of developing leptospirosis?



Pet shop owners

Field agricultural workers


Meat handlers

Slaughterhouse workers

Coal miners

Workers in the fishing industry

Military troops


Sewer workers

All the above


Answer: All the above

Which are portals of entry for the organism in leptospirosis?


Mucous membranes



The placenta during pregnancy

All of the above

Answer: All of the above

Endothelial Injury in Leptospirosis

  • The organism enters through the lymphatics into the blood stream and it causes endothelial injury to the blood vessel wall.
  • The endothelium is usually only permeable to water and electrolytes. When the integrity is lost and the gap junctions widen, the plasma and cells come out though the blood vessel wall causing edema and inflammation to the surrounding tissues.
  • The signs and symptoms will depend on which organ is involved as leptospira can easily enter organs like liver and kidney easily.

The reason/s for renal failure in leptospirosis is/are:

Interstitial nephritis

Tubular necrosis


All of the above


Answer: All of the above

The most consistent pathologic finding in leptospirosis is:

Vasculitis of capillaries

Endothelial edema


Lymphocytic infiltration

All of the above


Answer: vasculitis of capillaries

Which are organs which can be damaged by leptospirosis?





Blood vessels


All the above


Answer: All the above

Lung involvement in Leptospirosis

  • If there is vasculitis and endothelial dysfunction of the capillaries in the lungs, it can lead to life threatening complications as it leads to pulmonary congestion and edema or acute respiratory distress syndrome.
  • Most of the leptospirosis are mild cases and are not fatal whereas if there is involvement of the lungs, the prognosis becomes bad as there is high mortality among these patients.
  • Generally, if one survives the disease, though they experience long term illness and morbidity, most of them return to normal.

Leptospirosis - Summary

Leptospirosis may not be disease of the developed countries, but in India, we still get a lot of patients. Some of them develop serious complications and will be hospitalized for days together. They may need mechanical ventilation and dialysis during their hospital stay. Everyone who get exposed to the risk factors (especially the farmers) should be educated about leptospirosis and its complications

If you have any suggestions on this article or clarifications, please feel free to leave a comment.


    0 of 8192 characters used
    Post Comment
    • teaches12345 profile image

      Dianna Mendez 

      4 years ago

      I didn't even know this disease existed. I hope this helps someone avoid getting this awful condition.

    • aviannovice profile image

      Deb Hirt 

      4 years ago from Stillwater, OK

      This definitely is not something to fool with. We all need to take the time to take proper precautions from disease.

    • thumbi7 profile imageAUTHOR

      JR Krishna 

      4 years ago from India

      Hi Dr Pran Rangan

      Thanks for the visit

    • Dr Pran Rangan profile image

      Dr Pran Rangan 

      4 years ago from Kanpur (UP), India

      A well written hub in MCQ format. Thanks and well shared.


    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

    Show Details
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)
    ClickscoThis is a data management platform studying reader behavior (Privacy Policy)