Johannes Kepler- he was a great astronomer, astrologist, and German mathematician who was well known by the elite & worked for the hierarchy of his time, and revered as an instrumental component to the scientific revolution itself, as he revived such knowledge produced by a like mind as Aristotle on astronomy. He transformed such wisdom of Aristotle's, and formed it into a newer form of astronomy, which was soon seen as a sort of celestial physics by people of his time period. This eventually lead to the entire transition from the old ways of astronomy, to the more newer forms of seeing astronomy as being part of a more universal mathematical type of physics, as opposed to that of the old traditional physical cosmological one.
Christiaan Huygens - The inventor of the pendulum clock, Huygens was instrumental in many areas of science and mathematics, and including his influence on the developments of calculus. He was noted for his works using telescopic studies and discoveries of Saturn's moons. He also achieved great merit for his findings and understandings of light, and its peculiar ability to travel in waves, or by means of wave forms. This was one of his arguments he presented during his times, and became known as the Huygens–Fresnel principle. (Dealt with wave form propagation).
Leonardo Da Vinci - known mostly as a one of a kind painter and true renaissance man of his time, he was the most diversified mind of all great minds. Leonardo was not only a spectacular painter, but he was also a mathematician, scientist, architect, philosopher, musician, sculptor, engineer, anatomist, and the list goes on and on, according to Wikipedia. This guy was extremely talented in all ways one can imagine that's humanly possible pretty much, which sets him in a class entirely by himself. His artistry has stood out the most as a significant measure of his knowledge and understanding of the world of his times, and that of the universe as well, because much of it was celestial in its own design. He was most famous for his epic portrait known as the Mona Lisa.
Below are many of his amazing masterpieces
Sir Issac was brilliant indeed
Isaac Newton - He literally took the scientific revolution to the next level, by redefining the way the planets work and function in the universe. He is believed to be one of the greatest scientific minds of all time and his works set the precursors for many new sciences of his day which lead to further progress for the scientific communities worldwide. In his "Philosophiæ Naturalis Principia Mathematica", he laid the ground work for the foundation of classical mechanics, Newtons laws of gravitation, and Kepler''s laws of planetary motion. (referenced from Wikipedia)
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