Unless the venture is extremely well prepared, I would have to say an unequivocal no! Given that so much can go wrong in life on earth where we are adapted to live and whereas nature can be unforgiving of mistakes, we can in part rely on one another to carry us over the tough times. Anything going wrong on Mars would no doubt be fatal, even with help nearby. Here are some of the risks in a colony cut off from earth. A chance meteorite can ruin a whole colony. A cosmic ray burst event will deal a blow like up front exposure at Fukushima. Any technical breakdown could mean no oxygen, no water or no food as most of this would have to be obtained right on Mars and not imported at huge expense from earth.
Given the above, I think chances are better in near earth space, the moon or an earth crossing asteroid. If the going gets impossible, there is a better chance to bail out. The massive support network required to be built on Mars, just to support a few colonists is currently beyond our capabilities, especially seeing as we are still confined to low earth orbit. The cost would be astronomical and would have to invoke the bank accounts or the Rothschild family and as far as I know, they could not care less about space.
For now, I think robotic missions offer the most promise and maybe, they might get robots to manufacture the extensive infrastructure required for colonists, bet even this idea is remote. As for terraforming; we can't even get our own back yard straight. If we can't keep earth healthy as we unterraform it, how is it that we will terraform Mars?
I know there are risk takers out there who would jump at the chance, but I need much more insurance than is available for the foreseeable future. For now, for me, the answer is NO!