I like Christopher Nolan's take on the short story 'Memento Mori'. While it's not a full book, it is an interesting and challenging story to make into a film that I think he succeeds nicely at. The story is about a man who, after a terrible assault that results in his wife's death, can no longer commit short-to-long term memory. Regardless of this, he determines to find his wife's murderer, and as the story is in a first-person perspective, the reader is left to follow his thoughts only.
In a movie, however, the viewer is not forced to remember only what the character does but can in fact know more than the main character. Nolan's adaptaion, 'Memento', accounts for this and while the portrayal of the story is different, it is made in a very effective and ingenious way to follow the lead's feelings and how his disability has crippled him.