Growing up, my favorite cartoons were Ren & Stimpy and Rocko's Modern Life. I was also really fond of Dexter's Laboratory, The Powerpuff Girls, Ed Edd & Eddy, Johnny Bravo, and Samurai Jack. However, if Daria counts for the purpose of this thread (and I don't see why it shouldn't), it would be far and away the 1st Place winner.
If you asked me how I felt about modern cartoons a few years ago, I would have predicted nothing but doom and gloom, but with truly excellent shows like Avatar: The Last Airbender, The Legend of Korra, Steven Universe, Gravity Falls, Bob's Burgers, and Rick & Morty having come out just in the past few years, cartoons are better now than they've probably ever been. Phenomenal stuff coming out right now.