Be patient. She's 5. She doesn't even really know how annoying she is! You're older, you can out think her. Maybe. Make up games to play with her, so that she has to stop talking and think. Tell her every time she has a question, to write it down and when she gets to 5 or 10 questions give you the paper and you will answer her, on paper. But don't ever yell at her or tell her to shut up or that she is stupid.
I know someone who has a younger brother, they say when he was a child the only time he didn't talk was when he was asleep and even then they could hear him mumbling. Today he is an engineer and holds several Patents that have made millions of people's lives better. His older siblings still can't believe it and they could not be more proud.