With difficulty. It is the same as with a recent graduate with no experience. But at least the recent grad has some recent training. The mom that wants to go back to work doesn't even have that -- usually.
A letter of recommendation from a husband lauding the mom's housekeeping, bookkeeping, and day-care skills is not going to impress a hiring manager, regardless of her twenty-four years old MA.
All she is likely good for is some grunt job. If that doesn't make her happy, tough titties -- she set her course twenty-four years ago when she started pumping out spawn.
If she is in some creative field, she might be able to do something by assembling a knock-out portfolio to get a job or get some free-lance clients.