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Typhoid Fever Together with Dengue Fever: the Treacherous Tandem

Updated on June 28, 2016

Aedes eigypti, mosquito that transmits dengue fever virus

The incidence of dengue fever is again on the rise in the Philippines. As of today, the number of victims has surpassed the number of victims last year for the same period. There has been installed a device to trap mosquitoes developed by the Science and Technology department of the Philippines but it seems that it has no significant effect in controlling the disease. One factor that this is so could be the number of typhoons that had visited the country and the extent of flood that had been brought about by heavy rains. Dengue fever is listed as one of the diseases that is triggered by climate change.

Mosquito traps no doubt lessen the population of mosquitoes, the vectors of dengue virus. However, they have nothing to do with the virus. So far no vaccine has been developed against the virus. One reason could be that virus mutate so fast that a vaccine developed would be outdated within six months. Another reason could be that the framework used in developing treatments for dengue virus is inappropriate.

I suspect that the dengue virus is amenable to chelation. That is, an agent can bind with and remove the virus. Conventional medicine says that there is no control against the virus. However, the administration of vitamin C and supplements containing high level of chlorophyll has shown effectiveness in mitigating dengue fever if not controlling it. Vitamin C is a weak chelator, but a chelator nevertheless that can chelate out virus. Chlorophyll is a chelate of magnesium, that is, it contains a good amount of magnesium. This mineral is also a weak chelator.

A Filipino Internist and Chelationist

In March 2012, Dr. Arturo V. Estuita, MD, a Filipino internist and chelationist found that hepatitis B can be controlled by infusion chelation therapy. He administered this therapy on a fellow who had some 8 million virus in his body. In 8 to 10 chelation sessions, the virus count went down to 450,000, he told me. Now, the virus count went down to 10,000 virus in which case the virus is virtually harmless after a total of 35 chelation sessions, Dr. Estuita told me the last week of August this year. There is a new gadget that can give a virus count in four to five days. As news of his clinical results spread, some victims of hepatitis B came over for chelation and some 3 patients more had it.

In middle of May 2013 someone from a country in Europe came over to the Philippines for hepatitis treatment. I cannot divulge details of this treatment because it is confidential; details were not divulged to me either. Suffice it to say that the treatment was successful. This is the 11th case where infusion chelation therapy is applied successfully on hepatitis.

[This piece was formerly a part of a long Hub, "Possible causes of fever in toddlers; why fever is a welcome warning." However, I feel concerned about the victims of dengue fever that the message I wish to convey might be lost or muted in a long article. This is the reason why I decided to make it a separate Hub.]

New entries as of June 6, 2013

Dr. Estuita, MD has now treated 11 hepa B victims. I elaborate more on this topic in my Hub "A medical breakthrough in the control of hepatitis B by chelation therapy." That means the hepa V viron has a positive charge because EDTA has a negative charge (see diagram). EDTA forms a chelate with the viron. Dr. Estuita told me he had treated a dengue patient by infusion chelation therapy. (More of this below).

EDTA claws on a virion forming a chelate that is ejected thru urine

The treacherous tandem

This is the partnership between the dengue virus and salmonella, a bacteria. Dengue virus parasitizes salmonella. That is why dengue virus is also called bacteriophage or phage for short. The dengue virus consists only of RNA (ribonucleic acid) and is a retrovirus. This phage needs DNA (deoxyribonucleic acid) that it gets from salmonella to multiply into millions (Uno, G. et al, Principles of Botany. 2001:307). In other words, the virus commandeers salmonella; new salmonella now have the virus in their cell that burst and infect neighboring cells.

To repeat, microbes double their population every 20 to 25 minutes. The host cells turn into virtual dengue virus because their chromosomes had incorporated virus genes. Hosts, the infected human cells, now double their population every 20 minutes.

The victim is doubly unlucky if he gets both dengue virus and salmonella together. His fever is caused by the two during the gestation period of three to five days. For the infection, doctors administer antibiotics. The fever may subside but recurs. Why? The antibiotics had countered the salmonella but left the dengue virus growing in population and is now wrecking havoc. Antibiotics cannot kill virus. The virus attack the blood platelets that decrease in population dramatically from, say 350,000 to 150,000 to 80,000. This platelet count signals an imminent bleeding. And some patients in fact bleed who need blood transfusion. Doctors take pains to watch the platelet count. Dengue virus also attack the macrophage that is supposed to protect the body. Worse, macrophages with a virus load. along with the blood, now distribute the virus to various parts of the body. If salmonella were not controlled the dengue virus becomes more virulent by sheer rapid increase in population.

Symptoms of Dengue
Symptoms of Dengue | Source

The cost of hospitalization, about two weeks or more, of a dengue fever patient is high that the poor could hardly afford it. And to think that they are the most vulnerable having to live with degraded environment exacerbated by climate change. Caring for the dengue fever patient is also traumatic especially if you find blood oozing from the rashes and stools, and blood coming out of the mouth or eyelids. Sometimes the patient coughs up sputum with blood, an indication that s/he has internal bleeding. You are dealing with a hemolytic dengue virus, if knowledge of if is any consolation.

A daughter of ours had been afflicted with dengue fever when she was in grade school. Fortunately she did not get the bleeding type. She was treated with vitamin C at 500 mg per dose.

It is high time to conduct researches on the application of chelation against the dengue virus, using a framework other than the germ theory of disease.

The dengue viron has a positive charge. EDTA. the chelating agent has a negative charge. These charges attract each other that bind with and remove the virus complex. The chelation process is unlike the familiar reversible reaction in chemistry. EDTA (ethylene-diamine-tetra-acetate); has six pinchers like a crab (Walker, M. MPD. The Miracle Healing Power of Chelation Therapy. 1984:19-21). These pinchers claw on the virus complex. The chelate, composed of virus complex and EDTA, is ejected from the body through the urine.

That is how EDTA works in chelating out lead from the body. EDTA has been approved by the US Food and Drug Administration for use in remedying lead poisoning. It has been found to work for other diseases and disorders as well (Cranton, E., MD. Bypassing Bypass. Updated second edition. 1995)

New entries as of Dec. 29,2014

Another mode by which vitamin C treats dengue is as follows: Vitamin C is a precursor of hydrogen peroxide mediated by superoxide dismutase, an enzyme (Dr. Mercola. Internet. Dec. 29,2014). Macrophage shoots the dengue virus with hydrogen peroxide.

To recall, inducible nitric oxide, a free radical, kills cancer cells. This was found in an experiment on mice involving recombinant DNA technology. The inducible nitric oxide synthase was delivered by a virus vector riding on an antibody to cancer cells. When inside the cancer cell, inducible nitric oxide synthase produces nitric oxide that kills the cancer cell.

Hydrogen peroxide is a reactive oxygen species that acts like a free radical. Macrophage shoots bacteria using free radicals like bullets (Cranton, E., MD. Bypassing Bypass. Updated second edition. 1995).

In the case of dengue virus, there is no need to deliver hydrogen peroxide to virus-infected cells by way of antibody. It is the macrophage, a component of the immune system, that shoots the virus directly using hydrogen peroxide as bullets.


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  • conradofontanilla profile image

    conradofontanilla 4 years ago from Philippines

    My apologies to Dr. Tolstoy for taking the liberty to post here an email he sent me. I hope Hubpages allows this.

    Dear sir,

    I am a doctor from South India and writing a paper on dengue and typhoid in a patient. I had gone through your article 'Typhoid Fever and Dengue Fever: The Treacherous Tandem' which actually inspired me to write the report. I could not able to identify in the internet 'Uno, G. et al, Principles of Botany. 2001:307' journal or book, your are referring to? Can you please help me regarding this. If it is a book can be kind enough to mail the photocopies of the relevant pages for my reference.

    Thanking you,

    Warm regards, Tolstoy

    My reply to Dr. Tolstoy follows:

    Dear Dr. Tolstoy,

    I appreciate it that my Hub could help you. "Principles of Botany" is a book once borrowed from the library by my daughter who was taking up a course in Biology at the University of the Philippine Los Baños (UPLB). She had graduated. I could not get access now to the book. neither could she.

    I used that book as a reference in writing my book "Benefits Derived from PhilNONI" (2008). I am giving you part of the text

    "Dengue fever is a dreaded disease in the country today. What are the pertinent facts?

    (1) Dengue fever is caused by a virus transmitted by Asian tiger mosquito and Aedes aegypti species,

    (2) Virus mutates (changes) very fast. That is why the dengue virus today is different from the one some months earlier,

    (3) A dengue virus strain in, say, Polilio Island is different from that in Isla Verde,

    (4) A hybrid dengue virus can come out anytime: one parent came from a bird and bred with another parent in a person or pig.

    (5) This hybrid virus cannot be detected by the immune system of a person the first time he gets infected. The Memory cells built up in the first infection will detect the next one by the same hybrid. Some viruses (called bacteriophage, or simply phage) parasitize bacteria that serve as hosts on which phages multiply several times, like a factory (Uno, G. et al., 2001. Principles of Botany, page 307).

    (6) In the early phase of infection, symptoms are a mixture: that of dengue fever and typhoid fever caused by salmonella, a bacterium which antibiotics can control. In the 3rd to the 5th day symptoms of dengue fever become distinct. In clinical practice, patients with high fever and off-and-on fever are given antibiotics

    (7) Sometimes the disease turns out to be typhoid fever, other times it graduates into dengue fever. There are more cases when dengue fever does not develop when bacteria is apparently controlled

    (8) Antibiotics are ineffective against dengue fever in later stage, when the phage had already transferred its genetic material to the host by transduction. Through transduction, the bacterium becomes resistant (Pelczar, Jr., M. and R.D. Reid. 1972. Microbiology, page 391)."

    The pertinent text in which you might be interested is:

    "The Memory cells built up in the first infection will detect the next one by the same hybrid. Some viruses (called bacteriophage, or simply phage) parasitize bacteria that serve as hosts on which phages multiply several times, like a factory (Uno, G. et al., 2001. Principles of Botany, page 307)."

    (some text on brand name I deleted for this post)

    I am an alumnus of UPLB. However, I have not got a library pass so I could borrow the book. It will take me some time to obtain one.

    I am interested to read part of your report, if that is allowable and convenient for you.

    Dengue fever is a recurring epidemic in the Philippines and I am interested in putting a stop to it using the free radical theories of disease as framework. Chelation therapy is not yet widely accepted in the Philippines. It is applied in heart disease, diabetes, cancer, arthritis, and other degenerative or free radicals disease. Now chelation therapy is being used to control hepatitis B. I have three Hubs on this topic...."

    Warmest regards