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Blisters in Mouth - Symptoms, Treatment, Causes, Pictures

Updated on December 26, 2013

Pictures of Blisters in Mouth

What are Blisters?

Blisters are formations in the upper layer of the skin often filled with clear fluid known as serum although blisters can also be filled with blood or pus depending on which caused the blisters. Blister develops as the body’s response from an injury and trauma and is also the body’s attempt in protecting the underlying tissues by cushioning it from further damage during the process of healing. The balloon feature of blister is the result of serum rush towards the affected area in its effort for protection and facilitation of healing.

Blister can affect both male and female both children and adult while blister is a non-life threatening condition of the skin and often very easy to treat and manage. The size of blister varies depending on its cause and area of affected while the size can range from about a pinch size to a centimeter or more in diameter. There are three types of blister which are classified according to the fluid content of the pocket formation.

Clear blister

Clear blister is the type of blister filled with a clear fluid called serum or plasma. It is the most common type of blister while the serum contained in it is a vital component of blood in clotting process and blood cells as well.

Infected blister

Infected blister is filled with pus and is often resulted from injury or infection and is often painful when touched.

Blood blister

This is the type of blister that contains blood in the sac formed in the skin. This type of blister is the result of leakage of blood into the tissue after the small blood vessel located on top of the skin is damaged usually from a tight pinch on the skin or tight squeeze on the skin.

The formation of blister can occur in any part of the body although the foot is the most common area for blister growth. The mouth or the oral cavity can also be affected with growth of blister which can be painful and make talking and eating rather uncomfortable. Mouth blister is unpleasant and the development is usually in the part of the mouth with loose tissues such as the cheek, tongue, soft palate and the inner lip. Blister in mouth is more common I children although adults can also be affected. The onset of blister in mouth is often from trauma such as accidental biting of the lip. The onset can also arise from conditions such as fever and colds or from other underlying conditions. Blister in mouth is characterized by a tiny ulceration surrounded by a reddish halo and usually resolves on its own within a week.


Blister in mouth is painful and uncomfortable while talking and eating is rather difficult as brought by the painful lesion that developed in the mucosa within the oral cavity. Signs and symptoms may include the following:

  • Burning and tingling sensation in the affected area of the mouth
  • Development of sore or multiple sore in the mouth which is rather painful
  • Difficulty in eating and talking
  • Loss of appetite
  • Appearance of ulcer which is round in shape and whitish, grayish or yellowish in color and is bordered by a reddish halo.

Mouth blister can also get severe and the symptoms associated with the primary symptom of blisters include the following:

  • Onset of fever
  • Fatigue or sluggishness
  • Swelling of the lymph nodes


A lot of causes can be considered for the development of blister in the mouth. It is important to determine the cause of the blister to properly address its relief.

Trauma is the most common cause of mouth blister. Trauma includes incidental biting of the tongue or the cheeks during sleep or during food chewing. Biting of the lips and other areas or the mouth may also be the result of stress response which can be potential for blister.

Immune system depletion is another cause for blister such as the onset of fever blister or the cold sore. Blister that resulted from compromised immune system is often due to viral or bacterial infection and the sore developed as the body’s response.

Allergy in food and medicines can also result to mouth blister. Spicy and acidic foods can trigger the development of the blister while there are medicines which can dry the mouth subsequently blister.


While causes of mouth blister can be identified, no exact cure has yet identified except for some remedies to help relieve the symptoms. Mouth blister usually resolves on its own and should be given time to heal. It is therefore, necessary to avoid triggers of blisters while healing. Remedies and treatment may include the following:

  • Staying away from food and other irritants that can trigger blister.
  • Increase fluid intake to sufficiently hydrate the body.
  • Sufficient intake of Vitamin C especially during the onset of cold sore.
  • Natural remedy such as basil paste can help promote healing.
  • Enough rest and sleep to help strengthen the immune system.


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    • profile image

      Mary Addkison 

      19 months ago

      Blisters/ulcers in mouth/throat for 1.5 years. Saw primary-ENT-rheumatologist- doesn't know what/why. Continuous. Need help.


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