ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Cetyl Myristoleate: Who Discovered It

Updated on April 19, 2010

Who Discovered Cetyl Mryistoleate

Who First Discovered It?

Dr. Harry W. Diehl.  Dr. Diehl was employed by the National Institute of Arthritis, Metabolism, and Digestive Diseases. He was responsible for identifying and characterizing over 500 compounds, several of which were patented by the NIH.

His motivation to discover a way to help victims of arthritis began over 50 years ago when a friend, developed a severe case of rheumatoid arthritis and eventually became disabled.

Watching his long time neighbor and friend become crippled, Dr. Diehl embarked on a quest to find the reason and relieve the discomfort.


Quick Relief-CM Cream 

Topical Cream To The Rescue
Relives Arthritis Instantly 

OsteoArtiritis Knee Pain?

Don't Let Joints Freeze
Cetyl Myristoleate Works


Working on his own in his spare time, Diehl did his own experiments,  as cruel as it sounds, on mice. Unable to infect arthritis into mice, Diehl's research instincts told him that mice held the answers he was searching for.

Finally he found the factor - cetyl myristoleate, a member of the Omega 3 family of fatty acids.  It was something that mice had that people didn’t. 

This Omega-3, cetyl myristoleate, is an oil, is the hexadecyl ester of the unsaturated fatty acid cis-9-tetradecenoic acid. Diehl patented his discovery of cetyl myristoleate use for rheumatoid arthritis in 1977.

To prove his theory that mice are immune to arthritis because of this compound, Diehl and a colleague at NIH began to experiment on laboratory rats. Their research was published in the Journal of Pharmaceutical Sciences.

Diehl sought pharmaceutical companies to develop and market this newly proven compound, but because it was a natural substance and not a drug, none were interested.

Being a scientist, not a marketer, Diehl let his discovery lay dormant for about 15 years.

Osteo Arthritis


As Diehl got older, he began to experience osteoarthritis in his hands, his knees, and his heels. This is a form of arthritis that is general caused from an old injury or simply overuse of the joints.  Something linked to old age.

Dr. Diehl’s personal doctor tried the usual regimen of non-steroidal anti-inflammatory drugs and cortisone without much effect.

Out of curiosity and desperation, Dr. Diehl decided to try out cetyl myristoleate on his own form of arthritis.  He injected CM into his knee.

And it worked.  He was successfully treated and found relief from his own osteoarthritis.

Extremely impressed, Diehl’s doctor encouraged him to publish his findings and make it available to others.

After this was the time, CM was refined and introduced as a supplement instead of an injection.

In 1991 the commercial marketing of cetyl myristoleate began as a dietary supplement.

But again, Dr. Harry W. Diehl was no salesman, and the discovery went virtually unnoticed by the general public.


In 1994, the San Diego Clinic picked up the torch.

Their research staff did the first clinical study on cetyl myristoleate (CM or CMO). In it they proved that this Omega 3 Fatty Acid was of great benefit to osteo, rheumatoid, and reactive arthritis.

It proved helpful to nearly all forms of arthritis ---except gouty arthritis.

In Nevada December 1995, at the National Medical Conference on Aging, cetyl myristoleate was introduced to the medical community

Five doctors afflicted with a variety of arthritis conditions tried CM at the conference

Within three days, all five doctors responded successfully

The results are that hundreds of doctors began treating with CM on their arthritis patients.

It wasn’t until 2000 that more scientific studies were done, proving the effectiveness of CM in combination with other Essential Fatty Acids. 

Through double blind, placebo, controlled studies, documentation showed improvement in range of motion and overall function of patients with ostoearthritis.  And concluded that CM in combination with other EFAs "...may be an alternative to the use of nonsteroidal antiinflammatory drugs for the treatment of OA." Journal of Rheumatology. 2002;29:1708-12

Development of CM Continued

Research continued and a CM topical cream was introduced.  It’s relief was felt in as little as 30 minutes, but not as long lasting.

 Double blind, placebo, controlled studies, were again performed and confirmed the use of a topical CM complex cream as "effective treatment for improving range of motion and ability to ascend/descend stairs, ability to rise from sitting, walk and sit down, and unilateral balance." 

The Summary of this study states:

"Considering the increasing incidence of OA in the elderly population, pain-reducting medications such as acetaminophen, nonsteroidal anti-inflammatory drugs (NSAID), and COX-2 inhibitors have been common treatments. However, prolonged intake of NSAID increases the risk of gastrointestinal side effects and renal toxicity, and may inhibit synthesis of cartilage matrix. There is a need for alternative products that benefit patients with OA without harmful side effects." (J Rheumatol 2004;31-767-74)


Although Dr. Dielh first patented cetyl myristoliate for rheumatoid arthritis, these studies were done on patients with Osteoarthritis.

Dr. Dielh's mode for administering CMO was injection into the swollen joint. These studies proved along with the San Diago Clinic studies, the effectiveness of pills and creams.

This Omega 3 CMO fatty acid CM Complex may provide an alternative to NSAIDs and their side effects.


Submit a Comment

No comments yet.


This website uses cookies

As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

Show Details
HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
LoginThis is necessary to sign in to the HubPages Service.
Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
AkismetThis is used to detect comment spam. (Privacy Policy)
HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
MavenThis supports the Maven widget and search functionality. (Privacy Policy)
Google AdSenseThis is an ad network. (Privacy Policy)
Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
Index ExchangeThis is an ad network. (Privacy Policy)
SovrnThis is an ad network. (Privacy Policy)
Facebook AdsThis is an ad network. (Privacy Policy)
Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
AppNexusThis is an ad network. (Privacy Policy)
OpenxThis is an ad network. (Privacy Policy)
Rubicon ProjectThis is an ad network. (Privacy Policy)
TripleLiftThis is an ad network. (Privacy Policy)
Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)