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Human Aging: Free Radical Formation Theory.

Updated on June 10, 2013

Free Radicals

Free radical concept of aging discusses the biochemical phenomenon of aging. Free radical is an extra electron that creates a negative charge. The free radical has the ability to pair with other molecules in its attempt to find stability. Successful pairing of free radicals generates more free radicals which has the potential of damaging the cells in the body. Even though the effects of free radical have a negative effect, the body benefits from nerve conductions, energy production and immune responses.

Free Radicals Formation. Human Aging Free Radical Theory.
Free Radicals Formation. Human Aging Free Radical Theory.

The role of free radicals in the aging process occurs when the negatively charged electron attaches to cell membranes to produce waste products by the body. Metabolic waste has to be eliminated from the body because it is very toxic. Accumulated metabolic waste produces a toxic chemical called lipofuscins which darken the complexion of the skin. Age spot is a result of this phenomenon. Not only does lipofuscins alters the skin’s characteristics; it impairs cellular structure and functions by altering the DNA and RNA of the cells. It has a negative effect on protein synthesis which is vital for tissue repair, wound healing and muscle mass.

Free radicals are not new to the body and are a part of the destruction in the biochemical and physiological process in tissue repair and cellular replication as people age.

They are linked to the development of cancer because of their effect on cellular metabolism.

Furthermore, they have a negative impact on the production and function of natural elements in the skin that gives skin its texture and youthful appearance. Collagen and elastin are the major elements that maintain firmness of the skin which are destroyed by free radicals, giving rise to deep wrinkles.

Free radicals are associated with oxidization which is an interaction between oxygen molecule and other properties. Oxidization occurs in metals as well as body tissues and symbolizes the concept of aging.


Oxidization is a part of the normal physiological process of life and antioxidants are normally introduced to prevent this process.

Antioxidant is often consumed to fight against cancer and prevent cellular changes that are brought about by the oxidization process. Sources of antioxidants include:

  • vitamins C,
  • vitamin E,
  • grape seed extract,
  • pine bark extract,
  • red wine extract
  • and beta-carotene.

Other forms of antioxidant include flavonoids that are naturally produced in plants. They are very effective in the immune response such as performing phagacytosis that engulf invading microorganisms. They are effective in preventing cellular damages and diseases caused by free radicals.

Humans cannot produce flavonoids but they can absorb and utilize that of plant source.


Flavonoids are oligomeric proanthocyanidin complexes (OPCs) that are available in various forms and flavors for consumption as an anti-aging formula. The anti-oxidant formula provides easy absorption of OPC into the small intestine as it releases its benefits in providing anti-aging effects.

The most often used OPC is the isotonic form that can be mixed with water and allow rapid absorption. This allows the product to be absorbed without degradation that normally occurs in the small intestine. OPC-3 is a flavorful formula and isotonix OPC-3 is the most successful and popular OPC product available today.

These formulas are available on the internet which means that your cure for aging is just a click away. Anti-aging expert generally will offer naturally manufactured antioxidants to combat the effects of aging. There is also a substance called free-radical scavenger that see out free radicals and bind them to other molecules producing a cross-linking effect.


Theories of Aging

There are four basic theories of aging, (click to learn more):


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