ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Gastric Ulcer or Peptic Ulcer

Updated on December 2, 2013

Peptic Ulcer- An ulcer in the lower esophagus, stomach or duodenum can be commonly called peptic ulcers. Duodenal ulcers are not malignant, but about 5% gastric ulcers are cancerous.

The exact reason for the production of ulcer is unknown, but the various factors that can lead to ulcer:

  • Gastric hypersecretion: can be one among the reasons for the causation of peptic ulceration. Severe intractable peptic ulceration is found in patients having very high acid secretion. Reduction in gastric acid secretion by drugs helps in ulcer healing.
  • Acid Pepsin: Peptic ulcer is produced when the aggressive effects of gastric or duodenal mucosal resistance; as a result acid and pepsin of gastric juice digest the mucosa of stomach and duodenum.
  • Heredity: Ulcer patients often have a family history of the disease. Incidence of gastric ulcer in relatives is 2 times that of incidence in common population.
  • Mucosal Resistance: Gastric mucus, secreted by gastric mucus cells, coats the mucosal surface of the stomach. This mucosal barrier is broken by various agents like, alcohol, AIDS, acid reflux, aspirin, weak organic acids and decreased mucosal blood flow.

Difference between Gastric and Duodenal ulcer

Gastric Ulcer
Duodenal Ulcer
Usually single
May be multiple
After meals
In between meals
Gastric acid
Low or normal
Not relived by food
Relived by food
Commonly seen
In lower socioeconomic class
Equal prevalence
Chronic forms
May be benign or malignant
Usually benign

How to know that a gastric ulcer is malignant

  • Symptoms; Anorexia and weight loss, dysphagia, epigastric pain not related to food.
  • Signs

Epigastric mass

Metastasis indicated by; supra clavicular nodes, large irregular hepatomegaly, ascites, tumor of the ovary, deep vein thrombosis of leg.

  • Radiological showing: filling defect and failure of peristalsis in a site other than middle 2/3 of lesser curvature.

Very large ulcer anywhere in the stomach. Leather bottle stomach.

  • Gastroscopy and gastric cytology showing malignancy.
  • Gastric endoscopic US shows degree and extent of infiltration.


    0 of 8192 characters used
    Post Comment

    • dinkan53 profile imageAUTHOR


      6 years ago from India

      @beingwell Maintaining a diet that promotes an alkaline pH within the body is important for proper health. Thanks for the share and comment.

    • beingwell profile image


      6 years ago from Bangkok

      Shared this one.

      I'm acidic this really helps.

    • dinkan53 profile imageAUTHOR


      6 years ago from India

      @remaniki Thanks for your valuble comment and special thanks for sharing my hub.

    • remaniki profile image

      Rema T V 

      6 years ago from Chennai, India

      Hi dinkan53,

      As a person who is very much interested in health articles such as this one,I think everyone must get to read it. Great hub!Thanks for the knowledge. Socially shared.



    • dinkan53 profile imageAUTHOR


      6 years ago from India

      @BlossomSB Thanks as you found my hub as an useful one. What about your gastroscopy, hope every thing is fine and wish you good health.

    • BlossomSB profile image

      Bronwen Scott-Branagan 

      6 years ago from Victoria, Australia

      Thank you for an interesting hub. I'm off today for a gastroscopy, so it is timely! Voted up and interesting.

    • Injured lamb profile image

      Injured lamb 

      7 years ago

      Appreciate much for this informative hub that you have put your effort on the I have a clear picture of what a gastric ulcer is...shhhh...I have a gastric problem that always seem love to kill me...


    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

    Show Details
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)