- Diseases, Disorders & Conditions
Dementia as Caused by Human Immunodeficiency Virus (HIV)
How HIV causes dementia
Dementia is a feeling of being lost and forgetfulness.
It usually occurs during old age. It usually comes before the onset of Alzheimer's disease.
How does the human immunodeficiency virus (HIV) cause dementia? The answer is a long explanation.
HIV attacks when the macrophage is still young, called monocyte. Macrophage is a component of the immune system. It is the main bodyguard of the body. It engulfs foreign particles like virus and asbestos fibers. It also shoots bacteria with inducible nitric oxide, a free gas free radical.
Monocytes are produced by the gallbladder.
[That is also one reason why the gallbladder should not be removed in case of gallbladder stone. The best option is to dissolve the stone that consists of 80% cholesterol. Infusion chelation therapy can dissolve gallbladder stone.]
Monocytes mature into macrophage. It is during its monocyte stage that the HIV attacks the macrophage. The monocyte is vulnerable to the HIV.
Monocytes also enter the brain. A monocyte that contains HIV and enters brain brings along HIV into the brain cells.
HIV by itself cannot penetrate the blood-brain barrier. There are only a few substances that can pass through the blood-brain barrier. These are glutamate, glutamine, melatonin, glucose and chromium. A compound of glutamate, monosodium glutamate, can also get into the brain and cause lesions in brain cells.
Medical research found out that drugs cannot penetrate the blood-brain barrier, except urikinase, streptokinase, and T-pase. These dissolve blood clot used to remedy stroke.
Factory of HIV
Macrophage can multiply themselves very fast through cloning. Such multiplication is induced by the presence of foreign particles like asbestos, bacteria and virus.
Unfortunately, a macrophage that harbors an HIV also serves as a factory of HIV. As it multiplies itself, it also multiplies the HIV it contains.
Unfortunately still. the blood-brain barrier also protects the HIV from any drug that may be administered against the HIV.
Destruction of nerve cells
A nerve cell consists of axon, myelin sheath, dendrites and synapse. An axon is like a copper wire in electricity, the myelin sheath is like the insulation, dendrite is like a connection to another wire. Brain cells are not continuous. They are cut up into separate nerve cells each is also called neuron. There is a gap between two neurons. This gap is called synapse.
An impulse, like pain, travels from one neuron to another jumping through the gap by means of a bridge called neurotransmitter. That transmitter may be a mineral like calcium or serotonin.
HIV destroys the axon, myelin sheath , and synapse. If defective or totally destroyed the neuron cannot transmit an impulse or pain from the fingertip to the brain then back to the fingertip. Also neurons cannot transmit impulses between themselves. That is why forgetfulness or feeling of being lost occur. That is dementia.