ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Key Information About Colorectal Cancer

Updated on March 31, 2019
srirad0675 profile image

Srikanth is passionate about helping people improve their quality of life.

Overview

Colorectal cancer begins when healthy cells in the lining of the colon or rectum change and grow out of control, forming a mass called a tumor.

Source

Causes

The exact cause of colorectal cancer is not known, but it can be caused by DNA mutations that turn on oncogenes or turn off tumor suppressor genes.

This results in cells growing out of control. Changes in many different genes are usually needed to cause colorectal cancer.

Certain risk factors, including diet, tobacco smoking and heavy alcohol use, are strongly linked to the disease.

The risk of colorectal cancer increases as people get older. Colorectal cancer can occur in young adults and teenagers, but the majority of colorectal cancers occur in people older than 50.

Tests have shown that around a third of people who develop colorectal cancer also have the bacterium, which has the name Fusobacterium nucleatum. Their cancer also tends to be more aggressive, but it was not clear why until the recent study.

A paper that now features in the journal EMBO Reports reveals how the microorganism promotes the growth of cancer cells but not that of noncancerous cells.

Source

The blue cancer ribbon is symbolic of colon and colorectal cancer.

Symptoms

Symptoms of this cancer depend on its size and location. Some commonly experienced symptoms include blood in the stools and/or bleeding from the rectum, a change in bowel habit lasting longer than six weeks, severe stomach pain, lumps or a mass in the abdomen, weight loss, and fatigue.

Treatment

Due to advances in screening techniques and improvements in treatments, the death rate from colorectal cancer has been falling.

In general, patients with colon cancer receive post-operative chemotherapy if the lymph nodes are positive.

For rectal cancer, most patients who have positive nodes or who have tumors that extend into the fat surrounding the rectum receive chemotherapy plus radiation before surgery.

Treatment is also tailored to the patient's age, medical history, overall health, and tolerance for specific medications and therapies.

Source

Combining chemotherapy with targeted therapy helps improve outcomes in advanced stages, and pathway analysis is critical to planning treatment. Mutations in KRAS, APC, TP53 and extended RAS panels are some of the commonly studied alterations. The Cancer Genome Atlas Network and other research teams have identified newer set of genes that could be mutated in colorectal cancer, thereby contribute to treatment resistance.

— Dr. Sewanti Limaye

Prevention

Include vegetables, fruits, and whole grains in your diet. Avoid red meat and processed meats. Do yoga daily.

Since most colorectal cancer develops from non-cancerous polyps - growths on the lining of the colon and rectum - screening methods can detect and remove polyps BEFORE they become cancerous.

This content is accurate and true to the best of the author’s knowledge and does not substitute for diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed health professional. Drugs, supplements, and natural remedies may have dangerous side effects. If pregnant or nursing, consult with a qualified provider on an individual basis. Seek immediate help if you are experiencing a medical emergency.

© 2019 Srikanth R

Comments

    0 of 8192 characters used
    Post Comment
    • Eurofile profile image

      Liz Westwood 

      7 weeks ago from UK

      In the UK more has been said recently about screening for bowel cancer.

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://hubpages.com/privacy-policy#gdpr

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)
    ClickscoThis is a data management platform studying reader behavior (Privacy Policy)