ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Mosaic down syndrome; causes, symptoms, treatment, and prognosis

Updated on June 6, 2013

A drawing with emphasis on the common features of mosaic down syndrome

Source

Overview

Mosaic down syndrome is a subcategory of down syndrome, accounting for only 2-4% of all down syndrome cases. It is a rare form of down syndrome in which patients have two different types of cells in their body, one type of cell is normal (containing 46 chromosomes) and the other type of cell is abnormal (containing 47 chromosomes, the 47th chromosome being chromosome number 21); both types of these cells (abnormal and normal) are found as a mixture throughout the patient’s body. However, in the instance of non-mosaic down syndrome, a patient’s cells contain only one type of cell, cells with 47 chromosomes.

An extra copy of chromosome 21 is the root cause of down syndrome

Source

Causes

During early cell division, a misdivision occurs after fertilization of an egg cell. This misdivision results in mosaic down syndrome, where a person has a set of a normal number of chromosomes, and a set of chromosomes with an extra chromosome number 21. Usually, the chance of down syndrome occurrence in a baby is less than one percent. However, the chances of a baby developing down syndrome correlates to the age of the baby’s mother; a mother who is 35 years of age or older greatly increases the risk that her baby will have down syndrome if she is to conceive. This concept is primarily due to the fact that genes begin to deteriorate with age, and at 35 years and older, a mother’s genes have already started to deteriorate a while ago (around the age of 26).

Symptoms

The most common signs of a person with mosaic down syndrome are abnormal physical features, such as white patches in the iris of the eye, flat and straight hair, or a flat nasal bridge. Yet, beneath obvious signs on the surface, these patients typically suffer from either mild or moderate mental retardation.

Treatment

Before treatment can begin, this genetic disorder must first be identified with a simple blood test; often, this blood test is a standard procedure during pregnancy. After identification, patients can undergo mental and physical therapy programs and special educational and vocational programs, as a means of coping with a cognitive learning disability.

A long talk about down syndrome from two parents of down syndrome children

Prognosis

Despite an unfair setback early in life, these patients can improve their cognitive function and live a life like any other human being, with the help of family, tutors, teachers, and friends. Success is not a reflection of where a person started from, it is a reflection of where they end up, and mosaic down syndrome patients can be as successful as anyone else.

Know anyone with down syndrome?

Do you or does anyone you know have down syndrome?

See results

Comments

    0 of 8192 characters used
    Post Comment

    No comments yet.

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://hubpages.com/privacy-policy#gdpr

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)