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Noni Juice Mitigates Adverse Effects of Smoking
Noni fruit that yields noni juice
Antioxidants in noni juice catch free radicals and derivatives in cigarette smoke
Dyslipidemia and systemic inflammation are among the adverse effects of cigarette smoke. Smoking increases amount of high density lipoprotein, reduces amount of high density lipoprotein, increases fat in blood stream and increases amount of protein homocysteine. These result in oxidative stress. In turn, oxidative stress can result in tumor, cancer, heart disease, hypertension, stroke, emphysema and other degenerative diseases.
Dyslipidemia means high level of low-density lipoprotein (LDL) cholesterol, or low levels of high-density lipoprotein (HDL) cholesterol. Dyslipidemia is a risk factor for coronary heart disease and stroke. LDL contributes to plaque in heart artery, carotid artery and kidney artery. HDL is useful in that it escorts extra LDL to the liver for disposal.
Systemic inflammation is caused by a release of a lot of cytokines that spreads in the body. if untreated it can “ lead to organ failure and death” (The Merck Manual. Internet. Dec. 8,2014).
Inflammation is different from infection which is caused by bacteria, fungus, or virus. Inflammation is caused by free radicals and derivatives (more of this below).
Triglyceride is a type of fat in the blood stream. It is a risk factor in diabetes and heart disease. The normal level of triglyceride is 150, it is high when above 200 level (Medline Plus. Internet. Dec. 8,2014).
Homocysteine is a non-essential amino acid. It is made from essential amino acids. “ Elevated homocysteine levels have been associated with heart attack, stroke, blood clot formation, and perhaps the development of Alzheimer's disease” (Medline Plus).
In brief, oxidative stress occurs when the amount of built-in and supplemental antioxidants are overwhelmed by oxidants in the body.
The oxidants are free radicals and reactive oxygen species (ROS). Examples of free radicals are atomic oxygen, molecular oxygen, singlet oxygen, ozone, nitric oxide and superoxide. Examples of ROS are hydrogen peroxide, hydroxyl radical, alkoxy radical, peroxynitrite, nitrous oxide and hydrochlorous acid.
A free radical is any atom or molecule or fragment of a molecule with at least one unpaired electron in its outermost orbital. This is a path of electrons around the nucleus of an atom. For example, molecular oxygen has two unpaired electrons in its outermost orbital. A free radical is unstable and to stabilize itself it grabs another electron of a molecule in the neighbourhood. Such grabbing results in injury. This injury, usually done in the DNA (deoxyribonucleic acid), results in tumor or cancer. Grabbing does damage in cell membrane, inside parts of a cell resulting in degenerative disease. A ROS acts like a free radical.
Cigarette smoke is source of free radicals and radiation. In contains lead 2010 and polonium 2010 that are radioactive materials. Their presence in smoke was admitted by the cigarette industry in 1999 after hiding it from the public and smokers for over 50 years. The admission was forced by a series of lawsuits (Melpor. Polonium in tobacco leaves. Hubpages.com. Internet. Dec. 7,2014). Polonium decays into lead 206 that is stable. As it decays it releases energy and generates two unpaired electrons., Energy from radiation tunnels through barriers in hydrogen bonds in DNA, damaging DNA (along quantum theory). Such damage may result in tumor or cancer. Unpaired electrons grab electrons from molecules, usually of DNA, resulting in tumor or cancer or other degenerative diseases.
A study was conducted to find the effect of noni (Morinda citrifolia, L. ) juice on the blood serum (fluid). Some 132 persons, aged 18 to 65 years, participated in this study divided into three groups. One group was given 118 mL placebo (grape and blueberry juice without iridoids); another group was given 29.5 mL noni juice, with iridoids; another group was given 118 mL noni juice, with iridoids. The experimental design was double blind randomized with control, conducted in 30 days.
Participants smoked more than 20 sticks per day; had been smoking over a year; had not been taking antioxidant vitamins for over three months. They continued their smoking habit during the study.
Blood tests were done on participants once at the start of study and once at the end (Mian-Ying Wang , Lin Peng, Wedenbacker-Hoper, Shixin Deng, Gary Anderson and Brett. J. West. Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers. Scientific WorldJounal. Oct. 11,2012).
Conclusion of study
“Drinking 29.5 mL to 188 mL of noni juice per day significantly reduced cholesterol levels, triglycerides, and hs-CRP (C reactive protein). Decrease in LDL and homcysteine, as well as increase in HDL were also observed among noni juice drinkers.”
The placebo (without iridoids) did not affect blood fat.
“Noni juice was able to mitigate cigarette smoke-induced dyslipidemia, an activity associated with the presence of iridoids.
Noni juice contains more than 12 iridoids, two of them are deacetyleasperulosidic acid and asperulosidic acid. Iridoids in noni had been researched in 14 human trials. Its iridoids are constant that can be verified every time .
Iridoids in Morinda citrifolia are anti-cancer and anti-diabetic (Dr. Zsolt Petendi. Iridoids – A Pharmacists Prospective. Budapest, Hungary. Internet. Dec. 8,2014).
Noni juice may be effective in increasing the activities of glutathione peroxidase and glutathione reductase, according to Wang and associates.
Glutathione peroxidase turns superoxide, a free radicals, into safe water. Glutathione reductase recycles glutathione peroxidase.
Polonium 210 (half life of 138.4 days) comes from lead 210 (half life of 22 years). It means that lead 210 will supply polonium 210 for 44 years.
A person who quits smoking now will have lead 210 and polonium 210 in his/her body for 44 more years. This is the reason why a smoking quitter has to take iridoids at least that long.
I have yet to find a way to remove lead 210 from the body of a person who had accumulated it.