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PLUMMER VINSON SYNDROME

Updated on September 18, 2011
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WHAT IS PLUMMER VINSON SYNDROME ?

Plummer Vinson Syndrome is a condition in which chronic inflammation of upper end of oesophagus occurs, due to chronic hypochromic,microcytic anaemia.

It occurs in middle aged females and is characterised by dysphagia,anaemia,glossitis and additional features like Koilonychia, angular stomatitis and enlarged spleen.

WHAT IS THE PATHOLOGY ?

It is due to some peculiar reason.There is chronic inflammation at the upper end of oesophagus and there is fibrosis leading to dysphagia.In 30% of patients there is fissuring,cracking of mucosa,web formation and finally malignancy.

WHAT ARE THE SYMPTOMS ?

1) Weakness

2) Dysphagia

3) Patient takes longer time to eat

4) There are periods of complete remission

5) With treatment condition improves

WHAT IS THE INVESTIGATION ?

X-Ray shows partial stenosis of upper end oesophagus.

Oesophagoscopy confirms the condition.

WHAT IS THE TREATMENT ?

1) Prolonged treatment of microcytic hypochromic anaemia.

2) Repeated oesophagoscopy and dilatation.

3) Careful watch on patient's dysphagia.If it increases,there may be malignancy which in early stages is completely cureable.

WHAT IS THE PROGNOSIS ?

If malignancy ( post cricoid tumour ) has occured, Prognosis is Worst.The tumour is Radio-resistant and Surgery will be extensive. ( Gastrostomy ).

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