ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

About Pemphigus Vulgaris- Health Guide

Updated on May 13, 2013

What Is Pemphigus Vulgaris

Pemphigus Vulgaris is a serious yet rare skin condition that can take its toll on the human body if proper treatment is not sought out to control it in an appropriate manner of time. This is an autoimmune disease that is synonymous with erosions and sores located on the skin, most commonly positioned inside of a person’s mouth. Although this is not a very common condition by any stretch of the imagination, it is however the most common form of the pemphigus subtypes, as there are two other forms know as pemphigus foliaceus, and paraneoplastic pemphigus. While pemphigus vulgaris is not a disease that a person may concern themselves with on a daily bases, it is one that does not discriminate as it can certainly effect anyone at any time, no matter what race that someone may be a part of. However this disease does seem to be more common among individuals who are in the age range of fifty to sixty years old, and is a condition that has been more popular among Jews and Indians, as researchers believe this may be due to a genetic link that could pre-expose these types of people to the condition. This criteria does not mean that this disease cannot reach other races and various parts throughout the world.

Understanding Pemphigus Vulgaris

Many people may be unaware of the exact causes of this skin disease, and can often either overlook obvious symptoms or simply ignore them and try and treat them on their own. However, this is not a great plan of attack in order to rid you of this condition, as it would be a much more precise decision to seek adequate treatment and allow medical professionals to handle the situation. Being able to understand what is happening to your body in the first place is the most important step in your road to recovery, as this will allow you to initiate an eventual return to your normal self. The most crucial element in being able to fight off this nasty and annoying disease is to first be fully armed with a wealth of knowledge that will allow you to fully understand what this disease is and what it is exactly doing to your body. Understanding this disease, causes of this disease, the diagnosis, the treatments, and what your body will experience on its path back to healthiness is a necessary movement and one that cannot be underestimated by anyone who may be affected.

Symptoms of Pemphigus Vulgaris

Many people develop skin blisters in different areas of their body, as there are a variety of causes for different types of sores on the skin. However, when pemphigus vulgaris has made its way into your body, there are sever specific symptoms that you should consider noteworthy. For example, while often these blisters are located in the mouth, there are other areas on the human body where they will show up, as they will have several distinctive traits. Some common areas of the body where one may recognize these blisters include the scalp, armpits, general pressure points, the face, as well as the buttocks. The traits of these blisters to be aware of include an overall amount of sensitivity, meaning these blisters will be different than most in that they are easily busted and are generally loose and tender. After they have been burst, the affected area will normally be left severely raw causing a good amount of pain and a sore like feeling. They can also be very large, sometimes reaching up to several centimeters across, although there is normally no scaring on the area. In other instances, the larynx may be effected which will cause hoarseness and make swallowing a very difficult task.

What Causes Pemphigus Vulgaris?

Pemphigus vulgaris is an autoimmune disease which means that it occurs when the body tissues begin to attack their own immune system, thus forcing one’s body to produce antibodies against its own immune system. The antibodies that are produced in this scenario can damage the cells in the skin and mucous membrane located in the mouth, nose, throat, and genitals. They begin to attack the proteins in the body that holds cells together which causes the cells to fall apart. When the cells fall apart this will create a sore or blister on top of the skin. Though pemphigus vulgaris is generally found in only one member of the family, it has been suggested that the genes that are inherited from ones parents may make them more susceptible to the disease. In most cases PV is triggered from a bacterial or viral infection in the human body.

Diagnosis

Pemphigus vulgaris is a very rare disease that is most commonly overlooked by many doctors. However, when a doctor suspects that their patient have PV they will be referred to a dermatologist who will then confirm the diagnosis. This is a condition that should be suspected in anyone who may have a sore that will not heal which is in most cases located in the mouth. To confirm the diagnosis, the dermatologist will perform a skin biopsy called immunofluorescence. This test uses a dye to detect any PV antibodies in the cells and will measure the amount of those antibodies that are in the blood.

Treatment

Being told that you have a rare disease can be overwhelming and frightening, however there are several treatment options to choose from. In most cases treatment will involve taking a combination of two medications – steroid medication, immunosuppressant’s, rituximab, dapsone, colchicine, and tetracycline. These medications will prevent the immune system from damaging any more healthy tissue. While taking the medicine your body will begin to heal the blisters and prevent new ones from forming. Although both medicines can have several side effects such as weight gain, acne, mood changes, headaches, fever, fatigue, muscle pain, etc. Although pemphigus vulgaris is an extremely rare chronic disease, it can be treated with simple medication and love and support from your friends and loved ones.

Comments

    0 of 8192 characters used
    Post Comment

    • Gypsy Rose Lee profile image

      Gypsy Rose Lee 5 years ago from Riga, Latvia

      Thanks for sharing this informative hub. Had never heard of this.

    • MizBejabbers profile image

      Doris James-MizBejabbers 5 years ago

      Writercentro, I had never heard of this autoimmune disease, but neither had I heard of Henoch-Schonlein purpura until my son came down with it three years ago. Apparently my family (father’s side) carry the gene. These sound like very similar diseases. You didn’t say whether PV was potentially fatal, although the treatment was very similar to HSP. HSP is usually triggered by a bacterial infection and can be fatal. I guess I’m wondering if these two autoimmune diseases are connected. I found this hub very interesting and informative. Voted you up ++

    • always exploring profile image

      Ruby Jean Richert 5 years ago from Southern Illinois

      Interesting article, very informative. Thank you..

    • Ericdierker profile image

      Eric Dierker 5 years ago from Spring Valley, CA. U.S.A.

      Very interesting. I am now forearmed, thank you.

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: "https://hubpages.com/privacy-policy#gdpr"

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)