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Splenda Side Effects Under Investigation

Updated on February 21, 2014

Over the last twenty years, health conscious consumers have continually searched for a healthy artificial sweetener because of the health risks associated with a high sugar diet. The most concerned group of consumers being those who are seeking effective weight loss solutions. As heart disease, obesity and type 2 diabetes increased over the years, so have the availability of artificial sweeteners.

Each new artificial sweetener that became available gained popularity for a while until reports of serious side effects began to emerge. Before long many consumers had switched to the latest artificial sweetener claiming no side effects. Making a transition was always easy because the government declared that thorough testing had been done and the product in question was safe. This is the same government who has allowed trans-fats, food additives and genetically modified foods into our diet.

The latest artificial sweetener to come along claims to come from sugar and taste like sugar. It is known as sucralose with the trade name splenda. Splenda representatives state that no claims have ever been made that splenda is natural. However, when a public survey was conducted forty seven percent of people questioned about splenda believed it to be natural.

Splenda is anything but natural. Splenda representatives are quick to point out that splenda is not absorbed by the body and has no side effects. However, studies have found that eleven to twenty percent of the compound is absorbed. The chemical composition of splenda was formed by replacing three hydrogen-oxygen groups of the sucrose molecule with three chlorine atoms creating chlorocarbons, which is six hundred times sweeter than sugar. Chlorocarbons have a long history of being associated with reproductive, organ and genetic damage. Studies have shown that high concentrations sucralose cause shrinkage of the thymus gland in animals that most closely parallel human physiology.

There have been no side effects found with short term splenda use in the studies that have been conducted. However, the real concern is in long term effects of splenda. To date, there have been no long term studies conducted. Unfortunately, humans are once again made to be the guinea pigs for long term effects of a new artificial food substitute. It may well be that the serious side effects associated with long term, regular splenda use will not present themselves until the damage is done, as was the case with the artificial sweeteners that came before splenda. Potential side effects from health experts are believed to be liver, thymus glands, kidney, growth rate, weight and pregnancy problems. Splenda has also been found to significantly reduce intestinal flora essential to human health.

The truly healthy diet cannot consist of unnatural compounds such as splenda. There are natural alternatives to sugar that do not impact insulin levels and have no side effects. Two products that are highly recommended by health experts are stevia and xylitol. More information can be obtained about these substances by reading the The Dangers of Stevia.


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    • Meggan Tropos profile image

      Meggan Tropos 

      5 years ago from United States

      I was actually diagnosed with Fibromyalgia and suffered for nearly two years for what turned out to be an overdose of Splenda (I thought it was a "free" food and I used it freely!). All of my symptoms went away after I cut out splenda entirely. Now, years later, I can use it but am cautious about how much. It is not a free food - moderation is best for everything.

    • profile image


      7 years ago

      Could Splenda possibly cause a constant mucas in the back of the throat? I have used it for years in my morning coffee and have had this condition for years. I am in the process of changing to brown sugar just to see if it improves. Please let me know if anyone else has experienced this symptom.

    • fluffy42 profile image


      7 years ago from San Diego, CA

      Sucralose, even in very small quantities, causes severe gastrointestinal issues is a small percentage of the population. I have an article on the subject as well where I explain some symptoms.

    • dawnM profile image

      Dawn Michael 

      8 years ago from THOUSAND OAKS

      thank-you for sharring this improtant information, many of the man made products that have been processed are bad for the body, I alway try and use the raw natural forms of most products.

    • GarnetBird profile image

      Gloria Siess 

      8 years ago from Wrightwood, California

      I used to use alot of splenda, but switched to STEVIA, a natural herb. While on splenda I developed pretty severe thyroid problems. I wonder if it WASN'T a coincidence? hummm...good hub.

    • frogyfish profile image


      8 years ago from Central United States of America

      Just couldn't resist commenting again as I reviewed your hub. An acquaintance was questioning about splenda and I wanted some refreshing...

    • aefrancisco profile image


      9 years ago from somewhere down the road

      am surprise!... thanks for the info...

    • Jimmy Fuentes profile image

      Jimmy Fuentes 

      9 years ago from Rancho Cucamonga

      Great hub. A good site is .. I have seen it for years warning about splenda.

    • bradmauer profile image


      9 years ago

      Wow thanks for the information I have been using this stuff I guess its time to stop

    • stevemark122000 profile imageAUTHOR


      9 years ago from Southern California

      Good Cook, I did not mean to say that it has just been released only that it is the latest artificial sweetener on the market.

    • The Good Cook profile image

      The Good Cook 

      9 years ago

      Well, I'm confused. Splenda has been on the market for quite some years in Australia - has it only just been released in the US?

    • Kushal Poddar profile image

      Kushal Poddar 

      9 years ago from Kolkata,India

      I never believed in artificiality. Now I have a good reason.

    • Lady Guinevere profile image

      Debra Allen 

      9 years ago from West By God

      I have lots of that information on my hub about sugar and it's deception. It also has about Aspartame and the symptoms that it mimics and causes. I am sorry if some of you may think that I am promoting my hub for the point of being paid--not true, I just want to spread some truth about things and I have added this hub to my hub and hope others create a web of these hubs so all of us can get the knowledge that is being kept from us.

    • frogyfish profile image


      9 years ago from Central United States of America

      My opinion is that splenda will turn out to be as bad as its cousin, aspartame, which causes headaches, stomach problems, seizures and who knows what else...Stevia is wonderful and has been used for hundreds of years -ELSEWHERE. Finally got it to US - I heard recently that a major soft drink manufacturer was considering using stevia as a sweetner in a new drink? Anybody know? Thanks for this hub info!

    • Steve Orris profile image

      Steve Orris 

      9 years ago from NE Ohio

      I will go out of my way to aviod splenda.

    • stevemark122000 profile imageAUTHOR


      9 years ago from Southern California

      Thanks for your comments everyone! John, you can also buy pure stevia extract or the less expensive stevia extract with lactose sugar at your local health food store. You can also go online to

    • Lady Guinevere profile image

      Debra Allen 

      9 years ago from West By God

      John, You can buy the whole plant at  I have the link on my hubpage.

    • John Chancellor profile image

      John Chancellor 

      9 years ago from Tennessee

      Is stevia available in the US? Under what brand name? What are some of the major products that use stevia?

      Of course the obvious answer is to become aware of the sugar content in everyday products and realize that one 12 ounce can of most sodas will exceed the recommended daily sugar intake. If you want to eat/drink healthy, you must make some changes in your diet.

    • chicamom85 profile image


      9 years ago

      Thanks for info, my husband is a diabetic and uses it frequently

    • Lady Guinevere profile image

      Debra Allen 

      9 years ago from West By God

      Thank You for the information I was looking for and I added your link to miy hub:

    • men are dorks profile image

      men are dorks 

      9 years ago from Namibia

      Money, money, thats what its all about and screw the people or the one that might seriously need a superb product. Capitalism

      But I love it too(money I mean), unfortunately some one has to bear the consequinces

    • BkCreative profile image


      9 years ago from Brooklyn, New York City

      This stuff is truly bad news!

      Thanks for keeping us up to date!


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